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Gastroenterology (Expert Forum)
liver sgot/sgpt ratio, pancreatic enzymes and lipid profile questions
Answered by
Kevin Pho, MD - Internal Medicine
Kevin Pho, MD
Boston - MA
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/ Diverticulosis, Digestive Disorders, IBS, Stomach Pain.
liver sgot/sgpt ratio, pancreatic enzymes and lipid profile questions
by mastodons, Mar 25, 2006 12:00AM
Subject is 50 years old and weighs 253 pounds
Abused alcohol when 20-35 years old and then off
and on when 42-50 years old
Quit drinking for a number of years in 1990 after
in hospital:
principal diagnosis: acute and chronic pancreatitis
other diagnoses:
alcohol withdrawal
hypoxia
alcohol liver disease
E. coli sepsis
electrolyte imbalance (hypokalemia)
thrombocytopenia
Recent routine blood panel (with added
lipase and amylase and urine test) found
the following:
SGOT/SGPT 87/34 ratio 2.55
TBIL 1.7
AMYLASE 132
LIPASE 10
GLU 122
WBC 3
RBC 4
PLT 74
CHOL 104
TRIG 269
HDL 26
LDL 24
SPECIFIC GRAVITY URINE 1.008
BLOOD IN URINE 3+
Does high ast/alt usually suggest advanced
alcoholic liver disease?
Does moderate elevation of amylase suggest
chronic pancreatitis along with the low lipase?
He does have pale, smelly stools.
Are the low values in the blood connected
with liver or pancreas trouble?
What additional tests would you suggest?
fecal fat
trypsin
trypsinogen
Other tests you would recommend?
Would you recommend going to a gastroentrologist
or some other kind of specialist instead of family
doctor with these results?
Thanks
KathyT
Abused alcohol when 20-35 years old and then off
and on when 42-50 years old
Quit drinking for a number of years in 1990 after
in hospital:
principal diagnosis: acute and chronic pancreatitis
other diagnoses:
alcohol withdrawal
hypoxia
alcohol liver disease
E. coli sepsis
electrolyte imbalance (hypokalemia)
thrombocytopenia
Recent routine blood panel (with added
lipase and amylase and urine test) found
the following:
SGOT/SGPT 87/34 ratio 2.55
TBIL 1.7
AMYLASE 132
LIPASE 10
GLU 122
WBC 3
RBC 4
PLT 74
CHOL 104
TRIG 269
HDL 26
LDL 24
SPECIFIC GRAVITY URINE 1.008
BLOOD IN URINE 3+
Does high ast/alt usually suggest advanced
alcoholic liver disease?
Does moderate elevation of amylase suggest
chronic pancreatitis along with the low lipase?
He does have pale, smelly stools.
Are the low values in the blood connected
with liver or pancreas trouble?
What additional tests would you suggest?
fecal fat
trypsin
trypsinogen
Other tests you would recommend?
Would you recommend going to a gastroentrologist
or some other kind of specialist instead of family
doctor with these results?
Thanks
KathyT
Doctor's Answer
by Kevin Pho, MD, Mar 27, 2006 12:00AM
, Mar 27, 2006 12:00AM
To answer your questions:
1) An elevated transaminase level (i.e. AST and ALT) can signify advanced or early liver disease.
2) An elevated amylase level can be indicative of both chronic and acute pancreatitis. Imaging of the pancreas would be more helpful to determine chronic pancreatitis.
3) Low WBC, HgB and HCT levels can be associated with liver disease.
4) If the pancreatitis continues or worsens, you can consider an MRCP or ERCP to determine if there are any blockages in the bile ducts.
I would consider a GI evaluation based on these results.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
kevinmd_b
1) An elevated transaminase level (i.e. AST and ALT) can signify advanced or early liver disease.
2) An elevated amylase level can be indicative of both chronic and acute pancreatitis. Imaging of the pancreas would be more helpful to determine chronic pancreatitis.
3) Low WBC, HgB and HCT levels can be associated with liver disease.
4) If the pancreatitis continues or worsens, you can consider an MRCP or ERCP to determine if there are any blockages in the bile ducts.
I would consider a GI evaluation based on these results.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
kevinmd_b
Member Comments
by cljones, May 08, 2006 12:00AM
I am a healthy 43 year old female. I had a CT Scan done recently and was told I had a lesion on my liver that I should check out, I do not have any symptoms of any sort,nor have I had a cancer. I do have and appt. set up with Dr. I would not have known it was there had I not done the scan. Any opinions would ease my mind until Dr. appt.
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