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Gastroenterology (Expert Forum)
upper endoscopy results
Answered by
Kevin Pho, MD - Internal Medicine
Kevin Pho, MD
Boston - MA
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/ Diverticulosis, Digestive Disorders, IBS, Stomach Pain.
upper endoscopy results
by pellonmellon, Sep 27, 2006 12:00AM
I am a 40 year old female with sysmptoms of anemia, fatigue, gas and bloating, joint & muscle aches, and sometimes sharp pain in middle of lower abdomen as stool moves through. Had upper endoscopy with following results:
Visually, everthing fine
Biopsies:
“Microscopic Examination:
H&E and Giemsa stained sections of the antrum are reviewed. Control Giemsa stained appropriately. The gastric mucosa exhibits intestinal metaplasia, characterized by villous fronds covered with surface epithelium composed of alternating goblet cells and tall columnar cells. The mucosa is otherwise intact and is free of Helicobacter pylori organisms.”
“Final Diagnosis:
Antrum biopsy – Intestinal metaplasia with no Helicobacter pylori seen”
My questions are:
1. My doctor said this is a normal biopsy result, is that true?
2. For my symptoms and these results, what are the possible causes?
Visually, everthing fine
Biopsies:
“Microscopic Examination:
H&E and Giemsa stained sections of the antrum are reviewed. Control Giemsa stained appropriately. The gastric mucosa exhibits intestinal metaplasia, characterized by villous fronds covered with surface epithelium composed of alternating goblet cells and tall columnar cells. The mucosa is otherwise intact and is free of Helicobacter pylori organisms.”
“Final Diagnosis:
Antrum biopsy – Intestinal metaplasia with no Helicobacter pylori seen”
My questions are:
1. My doctor said this is a normal biopsy result, is that true?
2. For my symptoms and these results, what are the possible causes?
Doctor's Answer
by Kevin Pho, MD, Sep 28, 2006 12:00AM
, Sep 28, 2006 12:00AM
Intestinal metaplasia is a common biopsy result. This implies a reversible change of the cell due to an environmental insult. In most cases this is due to H Pylori, but is negative in this case. Other causes can include bile acid reflus as well.
There is no evidence of ulcers and cancer - in all, the biopsy does not show any acude disease.
As for other causes, the aforementioned bile acid reflux is possible. For bloating and gas, you may want to investigate the liver and gallbladder with an abdominal ultrasound, or consider a gastric emptying scan looking for gastroparesis.
These options can be discussed with your personal physician.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
kevinmd_
There is no evidence of ulcers and cancer - in all, the biopsy does not show any acude disease.
As for other causes, the aforementioned bile acid reflux is possible. For bloating and gas, you may want to investigate the liver and gallbladder with an abdominal ultrasound, or consider a gastric emptying scan looking for gastroparesis.
These options can be discussed with your personal physician.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
kevinmd_
Member Comments
by montiann, Oct 18, 2006 12:00AM
i have been having acid reflux for a while and i am scheduled for an endoscopy next week but i have been having this uncomfortable (not painful) feeling right under my sternum (like something is stuck). this mostly happens at night right before dinner. i am not sure if this is stomach related or stress over my symptoms.
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