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ALT and AST have dropped, still lots of liver pain?

Well, I'm still awaiting my next dr visit on the 26th, hopefully this new specialist will finally give me some flippin answers. Until then I'm searching desperately for answers myself. Please help me understand if you can....

Just about 4 weeks ago my ALT was over 2000. On the 1st of June it dropped to 1611 and as of the 12th it was down to 168. I guess I'm just not sure what that means. I still have liver discomfort and pain and try to deal with it as much as I can without taking the pain meds. I know my ALT was elevated by at least 1200 for over 5 weeks. I guess I just don't understand what that means exactly?! Does that indicate damage? dead liver cells?

Durning this time my AST were also highly elevated to well over 800 and is now down to 64.

I've done tons of research and some of it has just left me completely confused and with just more questions.

Like does anyone know if you can get chronic hep b from the Epstien- Barr Virus? I know it can cause hep b, but can it cause chronic?


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Avatar universal
Yes, I've been checked for autuimmune hepatitis the results were negitive. I've also been checked for everything suggested on that chart once the levels get so high, and all have been negitive. I've had 2 ultrasounds, a CT scan and a liver biopsy. The ultrasounds came out "normal" as well as the CT.

Up until I got smart the clinic kept telling me I had accute hep b. When the specialist dr explained the biopsy results over the phone she said "active hep b". I've done a google search on "active hep b" and it comes up as chronic. So, the last time I was in I asked to SEE the biopsy results from my regular dr. I saw them for maybe 30-40 seconds because it wasn't with my file so they had to find it. I asked why it said chronic. Her therory was that I had hep b awhile ago (sometime in the last two years, because my daughter does not have it) and when I got the EBV it caused the hep b to go crazy. HOWEVER, in reading the offical notes from that visit that came with the medical records yesterday that dr made NO mention of saying that to me, as I figured it was "off the record." They have since sent me to a GI specialist that I see next monday. I am not on ANY treatment thus far and am investigating whether or not I have an case to stand on against my previous clinic. There's more to it than just that, fwi.

If it is true that when a cell dies it releases the enzymes, a holy **** load of my cells must have been dying. My enzymes reached 2000 just before my liver biopsy, in which they did say I had severe damage... which makes sence now.

As you can see I'm on my own with this and have been trying to research all I can. I truley appriciate ALL the help because at this point between being exhausted 24-7 I only have a few hours during the day in which to research and try to make head or tails out of it. Thanks, VERY much.
Helpful - 0
Avatar universal
Looking at the chart with my highest ALT/AST only in the 200s it says Chronic Hep - which is correct.

I had no idea that they could get in the 1000s - now I feel like hey my doctor was wonky mine were LOW ;) (just kidding).

That was a very intersting read...

So it's great news that your enzymes went down so far I am so happy for you!

When a cell dies it releases the enzyme - so when your numbers were in the zillions it meant very bad mojo but now that you can see they have dropped so much - something good is going on!  You ARE on treatment?  If so Id say it's starting to work :)
Helpful - 0
86075 tn?1238115091
I second what Friole said, really good article on alts...although with a self-diagnosing hypochondriac like me, an article like that can be dangerous, ha ha! Just kiddin! (for the most part..)
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Avatar universal
goof - that was an interesting article on ALTs and ASTs

nirrti -- have you been tested for auto immune hepatitis?  It seems that the Epstein Barr virus can be a trigger for AIH hepatitis.  My sister in law had AIH and it took a long time to diagnose it.  Are you jaundiced?  Sorry that I know so little, but the treatment for AIH is about a 2-year round of steroids, and it is really important to do this.  Check out this article


http://www.emedicine.com/PED/topic181.htm
Helpful - 0
92903 tn?1309904711
<a href="http://www.aafp.org/afp/990415ap/2223.html">This might be of interest</a>.
Helpful - 0
Avatar universal
Thanks guys for your help. And yes I assure you they can get that high. At the highest my ALT was over 2000. They stop testing once it gets to 2000 by the way so we really don't know exactly what it was just that it definately got to 2000. At the same time my AST was the highest at 824.

I just requested and recieved copies of everything since this started May 5th. I really wanted to see the biopsy result, because that is the only thing I have seen with "chronic" on it everything else says accute. Wouldn't you know it to go with the shady medical attention I have gotten (not telling me wtf I have) they did not include a copy of the biopsy within the records I requested. I specifically requested the biopsy results when I called. Hrm.....

So now I have all the antigen and other tests, but I have no clue how to read them?! ANYONE know how, or a website where I could find this information?

I'm not sure this sounds to good either, in going thru the tests I tested positive for Epstien Barr Virus at 3099... It's on a similar scale as the ALT scale only normal for EBV is less than 20!!
Helpful - 0
Avatar universal
i do not think that the epstein-bar can CAUSE hep b, but it's possible that it can cause a flare up of an existing hep b condition.

check out the following website for more info on acute vs. chronic cases.  you should have a list of questions prepared for your follow up with your specialist.  this website will give you a good background on the lab tests and how to interpret results.

http://www.cdc.gov/ncidod/diseases/hepatitis/b/faqb.htm
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Avatar universal
I agree with NYgirl, I have never heard of #'s like that.  But even so, dropping to the 60's is great.  Ask your dr to explain every thing to you and write it down so you don't forget.  Better yet have a list ready with questions to ask him.

Good luck and let us know how you make out.

Beagle
Helpful - 0
Avatar universal
I have never heard of anyone with enzymes in the 2000s I didn't even know that was literally possible.  MIne were in only the 200s and my doctor went wonky because that was 'so high'.

If indeed somehow your enzymes DID drop from 2000 to only 64 I would imagine the inflammation is tremendous and the lining of your liver is what is causing the pain - but that would be a very GOOD THING.
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