Truvada and Kidneys

Question

My dad has been on Truvada for about 6 months now, his viral load has steadily declined however, his most recent blood test is indicate that the medication is affecting his kidneys; BUN Creatine 28.3.  He has no prior kidney conditions.  I know truvada affects kidney function, I was wondering if anyone else has any additional information / options on this.  Stopping the Truvada is not an option, and I am afraid to tinker with the dosage fearing a viral spike. I know the kidney function may be a "trade off" and I hate to say that.  We have been been through interferon, lumidivin/hepsera, all with initial success and then after awhile the viral load starts creeping up. The Truvada seems promising I just don't know, and can't find any further information regarding the extent to which kidney function is affected. Any information would be much appreciated. thank you.

shawn_hsp · Answer

If I'm not wrong, Truvada is a drug for HIV and AIDS, not a drug for treating Hep B. The current approved drugs for treating Chronic Hep B are:
*  Interferon-alpha (Intron A)
*  Pegylated Interferon (Pegasys)
*  Lamivudine (Epivir-HBV, Zeffix, or Heptodin)
*  Adefovir dipivoxil (Hepsera)
*  Entecavir (Baraclude)
and I don't see Truvada on the list

Kalio1 · Answer

So sorry your Dad is ill and you are dealing with this ilness and stress. This is a patient to patient forum, most of us have Hep C but there are no doctors here to answer questions just so you are aware of that. Do you mind giving a little more info? What are his stats and liver condition? What genotype does he have what is the history? Is he in a trial now? Lucky him to have such a loving, concerned daughter such as yourself caring for him.

Truvada and Kidneys

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