Questions in the Maternal and Child Health Forum have been answered by doctors from Henry Ford Health System.

Question Title: adrenal insufficiency and asthma control during pregnancy

Forum: The Maternal and Child Health Forum
Topic: Pregnancy - Abnormal


I have adrenal insufficiency and ashthma. Also chronic sinusitis. I want to get pregnant. What are the concerns related to these chronic conditions and their treatment during pregnancy on the fetus and for breastfeeding. Any special concerns for delivery? I am physically active, 42. I take regular replacement doses of hydrocortisone and oral zyflo and zantac for gastric reflux. Also medihalers including flovent, tilade, and combivent, as well as a regular antihistimine. Thank you for any information you can relate.

Dear Moise:

Adrenal insufficiency that is controlled with replacement corticosteroids will remain unchanged during pregnancy. The stresses that occur during labor will require increased corticosteroid coverage.

Asthma is more problematic. Approximately one third of women will experience a worsening of asthma during pregnancy and the reduced oxygenation of mother can be a threat to the baby (miscarriage, low birth weight, pre-term labor). Like most chronic diseases, if the disease is stable going into pregnancy the outlook is best; unstable chronic illness tends to exacerbate during pregnancy.

Whenever someone with chronic illness is contemplating pregnancy, a frank discussion with the physicians managing the illness and pre-pregnancy counselling with a Maternal Fetal Medicine specialist (an obstetrician who manages patients with medical complications of pregnancy) is advised. MFM physicians practice at referral medical centers: there are 4 such physicians based at Henry Ford Hospital (313-876-2454).

Keywords: Pregnancy, chronic illness

This information is provided for general purposes only and is not a medical consultation. If you have specific questions, please contact your physician.


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