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Mental Health  (Expert Forum)
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EFFEXOR XR and pregnancy
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD), bipolar disorder, dementia, electroconvulsive therapy (ECT), learning disabilities, memory, obsessive compulsive disorder (OCD), panic, personality disorders, phobias, post-traumatic stress disorder (PTSD), schizophrenia, stress, transitions, and work problems.

EFFEXOR XR and pregnancy

by Lerry, Oct 31, 2004 12:00AM
I've been taking Effexor XR for at least five years, and before that I was on another brand of anti-depressant.

      I have tried to wean myself off this medication before, as I hope to become pregnant, and it's effects on the unborn child were/are still unknown.

      I decreased from 150 mg to 75 mg, then spent about two weeks on 37 mg then stopped, but terrible withdrawl symptoms forced me to take it again 150 mg. I also kept taking the contraceptive pill.



       Recently, I tried to wean off it again, more gradually this time and spent over a month on 37 mg.

       The first and second days off it I suffered short 'eye-shakes' in one eye only. It was like everything was vibrating.

      The third day off I was extremely tired all day, kept going back to bed, felt depressed, fought with my parents, cried and had what other people describe as 'brain-zaps', (like sudden static electricity shocks).

      The fourth day off I went shopping and came home because I was feeling dizzy, as well as the other symptoms previously described.



       Should I go back on the 37 mg dose and have one every 2nd day, and then every 3rd or 4th day, and wean off it more gradually?  I no longer see that psychiatrist, who increased her fee dramatically and did nothing to improve my moods except prescribe me this shocking medicine, with no warning!



       Is anything known about the effects of this drug on unborn babies?  I am 39.

by Roger Gould, M.D., Nov 01, 2004 12:00AM
Yes you should wean yourself slowly on the scheudle you described.  You are also right about the risks being unknown, which means you should not be taking a chance.
Member Comments (20)

by Lerry, Nov 03, 2004 12:00AM
It has now been 7 days since I took my final Effexor tablet and it has taken this long to feel normal again.   That aint long compared to other stories I've read.  I now no longer get 'brain-jolts' (or whatever you want to call them), dizzy spells, eye shakes, crying fits. etc.



Time will tell if I suffer depression like I did before, but right now I feel great that I've beaten this poison!



I would like to suggest to other people who seem to be going through hell this way, that they wean off Effexor very, very slowly, (spend 2 months on each lower dose if that's what it takes), and if you suffer withdrawl symptoms once you're finally free give your body time to get used to the shock before you go back on the drug.



P. LERRY

by hangin'in there!, Nov 07, 2004 12:00AM
Oh dear! I'm in this situation myself.  I AM pregnant and still on effexor.  My doctor says it's not worth the risk and I should seriously consider weaning off it for a while.  I'm with him 100%!!! My husband agrees. My advice to pregnant women on meds. is discuss the risks and benefits with your doctor carefully and thouroughly and take the advice given by the expert.  A little concerned with withdrawl but am closely supervised by my GP so confident I'll get there.  Happy pregnancy!!!

by Lerry, Nov 09, 2004 12:00AM
To: Hangin'in there
I have read reports from people that have had perfectly healthy children while on Effexor, so don't panic!

Everyone's different.   You didn't say what strength Effexor you are on, but at least try to wean down in strength. Follow your doctors advice.

Best wishes to you and bubs!

LERRY

by hangin'in there!, Nov 11, 2004 12:00AM
Thank you, Lerry! Some reassurance and best wishes never goes astray - and I appreciate a kind word.



I was actually wondering how you are going with stopping effexor? Keep us posted, we would all love to hear that your transition to a med free future was a smooth one.



Have you looked at the other posts about effexor in this very forum? I think you would be blown away by the thread about effexor started by 'seektolearn'.  We are all guinae pigs! It reassures me to know some people do not get birth defects while taking effexor - could you show me where to find out more about this drug and pregnancy? Thanks again Lerry, and hope to hear from you again soon.

by cd26, Nov 20, 2004 12:00AM
i am on 75 mg and my doctor told me it was up to me if i wanted to come off this med, i'm also pregnant, and all my tests have turned out normal.  but i would very much like to come off of this, please help if you can thanks.

by hangin'in there!, Nov 20, 2004 12:00AM
Yes, I'm 5 weeks pregnant and on 75mg.  I think I will wean off it as I would love to breast feed this bub and do not want it to be born with withdrawl symptoms if nothing else.



cd26 how far along are you?  The doctor told me that physical birth defects would occur (if they were going to) during the first 8-10 weeks of pregnancy.  If I were to start withdrawing now I wonder if the damage would have already been done??



Good luck to you (and me) with effexor and pregnancy - it's a very hard decision to make and I am also reluctant to stop taking something that is helping me so much.  Let me know what you decide to do or email me at ts.***@****



Love from hangin'in there!

by WannaBAmama, Dec 08, 2004 12:00AM
I am interested in any and all information I can read on this topic.  My husband and I would like to start a family within the next couple years, but naturally I have my concerns.  I take 75mg of Effexor XR for anxiety and panic and have had excellent results.  The thought of going off the meds is very unappealing.  However, I want the best for my baby and would think going off would be a healthy chioce, esp. because then I could breast feed.  I ask myself everyday: Which would potentially do more damage: Stay on the meds and risk possible defects to the baby or go off the meds and make myself miserable and stessed, thus subjecting the baby to obvious stress?  I know I have time to think this over, but it's someting that crosses my mind nearly daily.

by zush, Dec 26, 2004 12:00AM
Hi,

I was pregnant with Effexor and thank god my baby is healthy. Try not to worry about it. I reduced my dose a bit but I still take it. Don't breastfeed your baby if you are still taking the medication.

Good luck!!!

by aprelbeck, Jan 04, 2005 12:00AM
I am weaning slowly from Effexor after 5 years.  Currently I am at 150mg to now 75 and hopefully soon NONE at all- have also been on daily dose of ADDERAll 30mg in AM, 30mg at NOON, 30mg at 4pm.  Cant believe i have finally broke this wretched addiction to what I once thought i couldnt function without.  I am 15 days and counting.  ROUGH, very Rough.

My Q:  Am switching to 37.5mg of Effexor in a week.  After that, is there any way to then SPLIT the 37.5 dosage as I continue a very slow weaning?  I am highly susuptible to Effexor's nasty withdrawal symptoms (hence the 5yr long addiction).  I have before been known to split the capsules and divy up the tiny little balls of medicine; however, each day is not a consistent dosage.  

Any one found any tricks/tips/hints on making the jump from 37.5mg to NADA without the bite?

thanks

***@****

by Chella, Jan 06, 2005 12:00AM
Hi

I have been on Effexor for 2 years and recently reduced from 150mg to 75mg.  I am turning 40 in March and also hope to try and fall pregnant before it is too late.  I am really struggling with fatigue, shock-like sensations, headache and anxiety.  I am so relieved to find that I am not the only one in this situation - I started searching the net yesterday, when I thought I was going mad trying to cope with the unpleasant withdrawal symptoms.  I have also gained 40 unwelcome pounds, which I hope to lose before I fall pregnant.



Another problem that I would appreciate some feedback on is this: My thoughts are very foggy and unfocussed.  I struggle to plan and get going with tasks that I have done 1000 times before.  I am easily confused and cannot cope with too much going on around me, especially if it is noisy.  At work I am sluggish and slow - it takes me ages to get my paper work done and to ensure that it has been done properly.  Do any of you have info about the effect of Effexor on thought processes and concentration?



I would appreciate hearing from anyone out there!



Thanks

Chella

by bubs84, Jan 23, 2005 12:00AM
I am 20 yrs. old, and I have been on Effexor XR for the past 2+ yrs. I have recently missed my period (over a week late), and I am elated to think that I might be pregnant! But with my joy comes apprehention and fear of the possible effects this drug may have on a developing fetus? My partner and I are excited with the possibility of pregnancy, but I don't think he knows what damage this AD can do to a baby!? Considering the fact that not even the makers of this drug know the effects! I believe that the best thing to do now is to lower my dosage (150 mg.) to 75 mg., to 37.5 mg. and so on. I hope for the sake of my (possible) child I am doing the right thing, and that the withdrawls aren't just as negative as the actual drug? I would love to know what you all think, any advice or knowledge would be so very much appreciated. I don't want to endanger my child just because I have a problem... I need some help!

by pgnhuntris, Jan 23, 2005 12:00AM
Hi All,

  I am 5 weeks pregnant and on 150mg Effexor XR. I suffer from depression/anxiety/bulimia. Where can I find more information on this drug during pregnancy and why am I reading that I shouldnt breastfeed? What substitute might be comparable and still let me breastfeed? Thanks, Barb

by ottosgrl, Jan 24, 2005 12:00AM
I too am on Effexor (150 mg/day).  However, my situation is slightly different.  I am bipolar, so I have a number of medications