I was diagnosed with MG about 14 years ago, my symptoms at that time were generalized muscle weakness, double vision, droopy eyes and fatigue while chewing. Shortly after this I had a Thymectomy. After about a year on mestinon I went into remision. I have had two flare-ups during this time involving the same symptoms that I presented with during my initial diagnosis. My most recent flare-up started about 2 months ago. During the 14 years since my diagnosis I have maintained a regular physical fitness regime when my MG is stable. This involves running, cycling, weightlifting(bodybuilding). I often participate in these activities up to 6 times a week. I am very involved in weightlifting and often push myself while working out; lifting as heavy a weight as I can handle on certain days. I am curious to know how this type of physical activity impacts my MG. Does pushing yourself to the point of muscular failure when weightlifting cause any negative effects towards my MG? Would you suggest lighter exercise? Would you suggest only light aerobic activity? What kind of exercise if any would you suggest. How often would suggest to be involved in any kind of exercise, if any. Thank you very much for time and knowledge. Stephen +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++=+ I have supplied a reference below which addresses the issue of exercise in myasthenia, for copyright reasons I cannot paste the body of the message. Lohi EL. Lindberg C. Andersen O. Department of Neurology, Sahlgrenska Hospital, Gothenburg, Sweden. Physical training effects in myasthenia gravis. Archives of Physical Medicine & Rehabilitation. 74(11):1178-80, 1993 Nov. The basic message is that exercise is beneficial in mild myasthenia even when the disease is active, I would not advise your type of exercise regime during an exacerbation, nor would I advise pushing yourself to the point of muscular failure in anybody, myasthenia or not ! I would not necessarily restrict you only to lighter aerobic activity, but would advise you to continue with weights, aiming for higher numbers of reps with lighter weights rather than your current regime. I would not suggest that you restrict the time spent exerciseing simply because myasthenia is in the background. Anyone who trains regularly knows when they are reaching a point of diminishing returns in terms of overtraining and fatigue. The guidelines are the same for you, you also can be guided by your own strength / endurance, stop if you are fatigued, continue as you are if you are feeling good, ( this applies within any one workout and over longer periods ). These end-points will fluctuate depending on the activity of your myasthenia. The bottom line therefore is that exercise is good within sensible giudelines between exacerbations you can follow as active a regime as anyone else, during a exacerbation ease off, and titrate your level of exercise the point at which you feel most comfortable.
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