Questions posted in the Neurology and Neurosurgery Forum have been answered by doctors from The Cleveland Clinic Foundation.

Question Title: Medication and ADD

Forum: Neurology Forum
Topic: Attention Deficit


My husband was dianosed with Adult ADD last year. He has tried Ritalin and Paxil. His Dr. does not like to use Cylert. The Ritalin created negative mood swings and depression. The Paxil did not seem to have any effect. Exercise seems to be the one thing that makes a positive difference in the typical ADD behaviors. Is there a medication that assists in the production of the chemicals present in the body during exercise or one that you might recommend trying next?


There are a number of medicatuions which have been used sucesfully in adults with ADD,
Cylert / Pemoline is one of them but there are a number of other options.
I have reviewed the published literature on the treatment of ADD in adults and found several alternatives.
A good deal of research has been published regarding the use of Venafaxime in this area and the reports are promising.
Another agent which has recieved attention with good reports is Selegiline which is also used to treat Parkinsons disease.
An older drug which is still used is Bupropion and success has been reported with the antidepressant agent Desipramine.
It is not possible topredict which drug willwork in any one person but if you are prepared tostart a seriesof theraputic trials there are options out there.





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