Posted by CCF MD on August 15, 1997 at 09:41:49:

In Reply to: Diagnosing Hereditary Spastic Paraplegia posted by Cheryl on July 28, 1997 at 13:03:46:

: I am trying to verify whether or not a blood test exists to diagnose
Hereditary Spastic Paraplegia (or Familial Spastic Paraparesis). I
have heard that there may be a blood test available for the X-linked
gene, but have not been able to verify that, or find out if tests
are currently available for any of the other genes.

American Journal of Medical Genetics 74 (1):26-36, 1997. Familial spastic
paraparesis: evaluation of locus heterogenicity, anticipation, and haplotype
mapping of the SPG4 locus on the short arm of chromosome 2.

Epilepsia 38 (4):495-9, 1997. A family with hereditary spastic paraparesis
and epilepsy. (review)

Good luck.