Question Title: 8 Years following 2nd meningioma surgery - seizures

My husband is a 63 yr old man who had his 1st meningioma cranial surgery in '86, 2nd one in
'90, and 3rd was Stereotactic Radial Surgery in '95. Since the '95 radial surgery, he has
gone thru 3 long periods of gran mall seizures. What I am beginning to notice is that when he is
excited, upset, in a large crowd, perhaps elevated blood pressure, a seizure takes place.
After surgery 2 - his left side was paralyzed for about 20 days. His tumors are in the front sinus.
I am starting to hear of those patients who had surgery 5+ years ago beginning a series of seizures.
Are there any studies on this? I am also beginning to notice that the site of the surgeries seems to
be collapsing a little bit. Does this happen with age? The seizures have lasted as long as 5 hours.
He is now having MRI's every 3 months to monitor any possible change. No change is noted since '95.
Please advise your thoughts or recommendations. Are there any studies he could be in?

Thank you, Bonnie Burke

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Thanks for the information. As you know meningiomas in general are benign tumors that arise from the coverings of the brain. They can, however, grow back and even invade into the brain. The fact that your husband has undergone 3 procedures would suggest that his tumor is more aggressive. I take it that he is on some type of anti seizure medication at this time? to help control the seizures. Changes in physiologic function can induce seizures in some places. Lack of sleep, anxiety, alcohol etc can lead to these spells. It is important that he keeps his blood level on antiseizure medication high enough. You can get skull depressions after surgery especially after 2 surgeries and radiation therapy - you could discuss this with your surgeon to determine if anything needs to be done. Some patients do undergo reconstructive surgery to repair these. There are clinical trials looking at medications for patients that have malignant meningiomas that show progression on MRI or CT scans but it does not sound like that is the case here. I think you need to discuss antiseizure treatment further with your doctor since that is a major concern. Good luck
This information is provided for general medical education purposes only. Please consult your docotor regarding diagnostic and treatment options.

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