Posted by CCF Neurology MD(B) on March 13, 1998 at 14:18:30:

In Reply to: Paresthesias: MS or Herpes? posted by Julie on March 01, 1998 at 03:24:44:

: I am 46-years old and have a probable diagnosis of MS (11 years; mild). I also have a 22-year history of Herpes Simplex I (outbreaks were terrible in the beginning but have been very mild and infrequent for many years), and a 14 year history of Herpes Simplex II (outbreaks have always been extremely mild). A symptom that I have been experiencing off and on for several years (at least 9 years) is patches of burning sensation on the outer surface of my skin (feels just like a sunburn). These patches vary in size and intensity, and are often along my upper thigh, buttocks, or waist, but can also be on my cheek (very painful), arm, or other miscellaneous places. The size of the patch seems to be directly correlated with the length of time that the sensation lasts (usually no more than a 3-5 days). The size of the patches vary from a few square inches to as large as the entire side of my thigh. Importantly, there does NOT appear to be a temporal correlation between Herpes outbreaks and these burning sensations. However, I could be wrong because, again, my Herpes outbreaks (I and especially II) are now so very mild. I have two questions: Can Herpes I and/or II cause the symptom I have been experiencing, or is it more likely caused by the MS? Secondly, if there WAS a temporal correlation between the Herpes outbreaks and the symptom, would that change your opinion? Thank you so much for taking the time to answer my questions. I am very appreciative.

Sincerely,
Julie
=Dear Julie, I am not so much concerned about a temporal relationship as a spatial one. If the pain occours in areas were you have had prior herpes infections, I would consider this to be related to your past Herpes infections. However, if there is no relationship, I would believe that your history of MS is the more likely cause. Hope this helps. "This information is for educational purposes only. You should always consult your doctor for diagnosis, treatment options and prognosis."