Questions posted in the Neurology and Neurosurgery Forum have been answered by doctors from The Cleveland Clinic Foundation.

Question Title: MG pregnancy and miscarriage

Forum: Neurology Forum
Topic: Myasthenia Gravis


I suffered a mc in February and was considering conceiving again. I would like to know if there is a conncection between MG and pregnancy loss. Specifically, if there is a higher incidence of immune acctivity that may attack and kill a baby. Even more specifially, the validity of Natural Killer cells and there effect on MG and pregnancy.

Thanks in advance

Carrie


There is no evidence that Myasthenis causes an increased incidence of
miscarriage, antibodies do affect the newborn in about 20% of cases and may
cause a mild transient myasthenia in the first few days of life.
The other problems are that the myasthenia may undergo exacerbation in
pregnancy and prolonged labour is not possible, so early consideration of
cesearian section is frequent.
There is no evidence however that there is a higher incidence of miscarriage
mediated by natural Killer T cells or otherwise.
As regards the "validity " of natural killer cells this is a dramatic name
for activated blood cells which are part of the normal immune response in everyone
and there is no link with miscarriage.
Related Communities
Neurology
Sleep Disorders
Migraines & Headaches
Degenerative Diseases
Cerebral Palsy
Parkinsons Disease
Epilepsy
Tourette Syndrome

[Neurology Forum]      [Neurology Forum Archives]