Questions posted in the
Neurology and Neurosurgery Forum have been answered by doctors from The Cleveland Clinic Foundation.
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Subject: Re: MYASTHENIA GRAVIS
Hello, D, The treatment of myasthenia gravis involves careful use of anticholinesterases and immunosuppresants. The later includes prednisone. As far as the interaction of prednisone with aspirin, based on my literature search, prednisone may decrease the serum concentration of aspirin, which in turn potentially decrease the effects of aspirin (J.Clinical Pharmacology, 26:334:1988). However, this usually does not warrent the discontinuation of either. Careful clinical monitering, in my opinion, should be sufficient. Your question on the association between TIAs and MG is a difficult one. It has been documented that the two diseases can mimic each other to a great deal. This generally requires much more careful evaluation. Please be advised that our department is nationally well known for specializing in both stroke, led by Dr. A.Furlan, and MG, led by Dr. K. Levin. You will benefit the most if you can come to Cleveland Clinic for a full outpatient visit. Please call toll free (800)223-2273 or (216)444-2200 ext.45559 for an appointment at your earliest convenience. Hope to see you soon. This information is provided for general medical education purposes only. Please consult your primary physician for the diagnosis and treatment of your specific medical condition.
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