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Neurology (Expert Forum)
Paroxysmal Neuro dysfunction/ Basal Ganglia
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Paroxysmal Neuro dysfunction/ Basal Ganglia
by Kathleen, Jan 20, 2000 12:00AM
Thank You for taking my question.
I have seen a neuro doc for second opinion concerning "seizure like" episodes that started many years ago. The opinion is that I
show symtoms sugggestive of basal ganglia dysfunction as well as
possible mitochondrial disorder. Further testing has been sugested.
Although I was able to locate the Mito disorder that was referred to , I cannot locate anything on Basal Ganglia. Could you help describe this type of disorder please?
I have seen a neuro doc for second opinion concerning "seizure like" episodes that started many years ago. The opinion is that I
show symtoms sugggestive of basal ganglia dysfunction as well as
possible mitochondrial disorder. Further testing has been sugested.
Although I was able to locate the Mito disorder that was referred to , I cannot locate anything on Basal Ganglia. Could you help describe this type of disorder please?
Doctor's Answer
by CCF Neuro[P] MD, RPS, Jan 20, 2000 12:00AM
Dear Kathleen:
Basal ganglia are responsible for control of motor movements, they act in concert with the cortex to smooth out movements. Diseases of the basal ganglia give certain types of movement disorders such as dystonia, choreathetosis, chorea, etc. Diseases such as mitochondrial cytopathies, Wilson's, Hunington's, essential tremor, Parkinson's etc have all been related to having a connection with the basal ganglia. Many mitochondrial disorders effect the basal ganglia, but not all. Even the same type of mitochondrial disease (i.e. MELAS) may or may not affect the basal ganglia.
I hope this helps. There is a mitochondrial web site from the United Mitochondrial Foundation you may want to visit.
Sincerely,
CCF Neuro MD
Basal ganglia are responsible for control of motor movements, they act in concert with the cortex to smooth out movements. Diseases of the basal ganglia give certain types of movement disorders such as dystonia, choreathetosis, chorea, etc. Diseases such as mitochondrial cytopathies, Wilson's, Hunington's, essential tremor, Parkinson's etc have all been related to having a connection with the basal ganglia. Many mitochondrial disorders effect the basal ganglia, but not all. Even the same type of mitochondrial disease (i.e. MELAS) may or may not affect the basal ganglia.
I hope this helps. There is a mitochondrial web site from the United Mitochondrial Foundation you may want to visit.
Sincerely,
CCF Neuro MD
I am curious if you don't mind me being nosy. What are your seizures like. What happens and how are they related or unrelated to the text book ones? How long do they last? The reason I ask is I have had numerous seizure like events over the past three months related to alcohol withdrawal but not the usual generalized type.I have had no explanations from doctors.
Thanks,
Barbara
CCF Neuro MD