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Neurology (Expert Forum)
Thyroid hormone imbalances or neuro disorder?
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Thyroid hormone imbalances or neuro disorder?
by wvopstal, Jan 11, 2005 12:00AM
I am a 36 yo M. After thyroidectomy (thyroid CA) in 08-2004, I was immediately started up on 175mg T4, and upped to 200mg. On 7 Dec, my TSH was <0.01 and FT4 27.
A few weeks after starting T4, I very rapidly developed pains and aches in proximal muscles and along both sides of my trunk. This was accompanied by fatigue and some weakness. The weakness seems to have started a few weeks following the pains and aches. This was accompanied by occasional fasciculations - short 'plopping' sensations in random locations. Never more than two, three twitches at a time, and about a dozen to two dozen times a day. These have since become a lot less and are only sporadic.
I have however still a lot of pain along the left shoulder levator scapula and rhomboids. The left arm often feels tired and achy and I have to put down heavy objects more quickly than on the right arm. The bi/tri-ceps sometimes twitch. The pain and fatigue in the other areas is still there, but somewhat improved.
My endo thinks with an FT4 of 27 I should be doing better and did further tests. These revealed a CK of 270. He's not particularly worried, but wants an EMG.
- I was under the impression that marginally elevated CK is a feature of hypo-, not hyperthyoidism?
- Is an FT4 of 27 to be considered as hyperthyroidism?
- I have recently had to stop T4 for four weeks due to a I131 scan and during that time, my symptoms got significantly worse again. Does that make sense?
Is is all due to hormonal balances and how long will symptoms drag on? Am worried about other serious neurological disorder. Thx.
A few weeks after starting T4, I very rapidly developed pains and aches in proximal muscles and along both sides of my trunk. This was accompanied by fatigue and some weakness. The weakness seems to have started a few weeks following the pains and aches. This was accompanied by occasional fasciculations - short 'plopping' sensations in random locations. Never more than two, three twitches at a time, and about a dozen to two dozen times a day. These have since become a lot less and are only sporadic.
I have however still a lot of pain along the left shoulder levator scapula and rhomboids. The left arm often feels tired and achy and I have to put down heavy objects more quickly than on the right arm. The bi/tri-ceps sometimes twitch. The pain and fatigue in the other areas is still there, but somewhat improved.
My endo thinks with an FT4 of 27 I should be doing better and did further tests. These revealed a CK of 270. He's not particularly worried, but wants an EMG.
- I was under the impression that marginally elevated CK is a feature of hypo-, not hyperthyoidism?
- Is an FT4 of 27 to be considered as hyperthyroidism?
- I have recently had to stop T4 for four weeks due to a I131 scan and during that time, my symptoms got significantly worse again. Does that make sense?
Is is all due to hormonal balances and how long will symptoms drag on? Am worried about other serious neurological disorder. Thx.
Doctor's Answer
by CCF-Neuro-M.D.-CS, Jan 14, 2005 12:00AM
I cannot give a clinical diagnosis over the internet
Also, I am not an endocrinologist and cannot give you expert advice on the results of your thyroid function tests
Hyperthyoidism can cause a myopathy or proximal muscle weakness with fasciculations, so the T4 may be resposible for those. It is less clear what the other symptoms are.
A marginally elevated CK is quite non-specific but could could be due to hyper or hypothyroidism
You need to consult with your endocrinologist about the thyroid questions. Usually a set of symptoms can be explained by one unifying diagnosis rather than two completely seperate ones
If you are concerned that you have aneurological disorder you should seek a consultation with a neurologist. The EMG may reveal more also
Good luck
Also, I am not an endocrinologist and cannot give you expert advice on the results of your thyroid function tests
Hyperthyoidism can cause a myopathy or proximal muscle weakness with fasciculations, so the T4 may be resposible for those. It is less clear what the other symptoms are.
A marginally elevated CK is quite non-specific but could could be due to hyper or hypothyroidism
You need to consult with your endocrinologist about the thyroid questions. Usually a set of symptoms can be explained by one unifying diagnosis rather than two completely seperate ones
If you are concerned that you have aneurological disorder you should seek a consultation with a neurologist. The EMG may reveal more also
Good luck
