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Neurology  (Expert Forum)
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frequent muscle fatigue and ache
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frequent muscle fatigue and ache

by J43, Sep 25, 2005 12:00AM
For several years I have experienced muscle ache and fatigue primarily in my hamstrings.  The conditions will diminish for several months and then return for several months. The severity is such that short walks (5 min) leave me feeling exhausted and I cut back my normal exercise routine.  I am a 43 yr old male with no other health problems.  My GP has given me all the usual tests and nothing has turned up. I get plenty of sleep, eat healthy, no extreme stress.  What can be causing this?  I feel like an old man.

by CCF-Neuro-M.D.-PW, Sep 30, 2005 12:00AM
The potential cause may not necessarily be neurological (the topic of this forum)

Important causes such as peripheral vascular disease need to be tested for with pulse doppler ultrasound of the legs. Rapid relief of symptoms on resting would suggest this cause. Heart and lung problems causing reduced exercise tolerance should also be excluded.



Muscle aching with exercise can in rare cases be caused by metabolic muscle disease - partial deficiencies of muscle enzymes that are actiuve with exercise. Testing includes blood tests for creatine kinase, urine testing for blood after exercise, and if considered by your doctor or if an needle EMG study showed evidence of mscule disease, a muscle biopsy may be necessary to prove it.
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