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Urology (Expert Forum)
Hypospadias
Questions in the Urology forum are answered by Dr. Stephen Liroff, affiliated with the Henry Ford Hospital. Topics covered include benign prostate disease, penis curvature, cystisis, kidney stones, pediatric urology, prostate, sexual dysfunction, urinary tract infections (UTI), and urological cancers.
Hypospadias
by J. Harold, Aug 14, 1999 12:00AM
My 21 year old son had a mild hypospadias repaired as a toddler. He seems to be the only occurence of this defect in the family. We have been told that he has a slightly higher than average chance of passing this defect on to his own offspring. Is there a relationship between this congentital defect and others such as intersex, cryptorchidism, other midline defects? Is he at any greater risk of fathering a child with these problems? We also have a son who is gay. Is there any genetic relationship between hypospadias and homosexuality? Thank you.
Doctor's Answer
by hfhs M.D.-AK, Sep 02, 1999 12:00AM
Dear Harold,
The incidence of hypospadias has been calculated at 1 in 300 live male births. In the US, about 6000 boys are born each year. Familial tendencies indicate some genetic factors due to the fact that fathers with hypospadias have an 8% chance of passing the defect on to each male child he fathers. Also, 14% of male siblings are affected. This condition is more common in whites than blacks.
The most common associated anomalies would include undescended testes and inguinal hernia.
Other less common associated anomalies include upper urinary tract defects. It is recommended that all patients with hypospadias have their upper urinary tracts evaluated to some degree.
In reguards to intersex. Hypospadias is thought to be a form of intersex. Certainly the diagnosis of classic intersex must be ruled-out in cases of severe hypospadias, especially those with associated undescended testes.
Your last question I can only respond to with the comment that there is no know study or research to support the statement that homosexuality and hypospadias are linked in any way.
Member Comments (2)
by Mark, Aug 16, 1999 12:00AM
To: Pediatric Urology
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by Mike, Aug 16, 1999 12:00AM
To: Pediatric Urology
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