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Urology (Expert Forum)
elevated cpk levels what is it?
Answered by
Kevin Pho, MD - Internal Medicine
Kevin Pho, MD
Boston - MA
Questions in the Urology forum are answered by Dr. Stephen Liroff, affiliated with the Henry Ford Hospital. Topics covered include benign prostate disease, penis curvature, cystisis, kidney stones, pediatric urology, prostate, sexual dysfunction, urinary tract infections (UTI), and urological cancers.
elevated cpk levels what is it?
by kakarot, Apr 06, 2004 12:00AM
im a 20 yr old male. i was an athlete up untill 4 yrs ago....then i started smoking everything under the sun every day for 4 yrs...i rehabilited a year ago (i am on serequel((anti psychotic)) 400mg and apparently its not that that is affecting my results) and since then i have tried to go to the gym but after 3 sessions i noticed i was fatiuging. i went and got a blood test and my cpk level was 2789, 3899, then 5268 (3 days between each test) i then waited 2.5 weeks and the results dropped back to 106. (my liver function test was a little high) i attended gym again and posted similar results after. i then had a muscle biopsy and my biochemistry results were all normal except my PMCR AKCR were slightly high (2.71 for both, ref rge is .7-2.20 and .25-1.50 respectivly) i havnt got any other results back yet and in suspense. have you any idea what it might be? or how i might be able to keep it down? so i can train hard.... thanks heaps kakarot
Doctor's Answer
by Kevin Pho, MD, Apr 07, 2004 12:00AM
, Apr 07, 2004 12:00AM
Creatine kinase is an enzyme found in the heart, brain, and skeletal muscle. CK in the blood comes mainly from your muscles.
An elevated creatinine kinase can be suggestive of a variety of muscle disorders. Here are examples what some diseases that you may want to discuss with your personal physician.
Included in this group are motor neuron disease (amyotrophic lateral sclerosis), myasthenia gravis, the muscular dystrophies, and the various inherited, metabolic, drug�induced, endocrine, infectious and other inflammatory myopathies.
The muscle biopsy is a reasonable next step. You may also want to consider an EMG. Other considerations would be a rheumatology consult if the muscle biopsy is not revealing.
Other lab tests to consider are aldolase, lactate dehydrogenase, and the aminotransferase levels.
I am not familiar with the PMCR/AKCR abbreviations - it is possible that they are different terms from what I am familiar with.
Bibliography:
Miller. Clinical manifestations and diagnosis of adult dermatomyositis and polymyositis. UptoDate, 2004.
An elevated creatinine kinase can be suggestive of a variety of muscle disorders. Here are examples what some diseases that you may want to discuss with your personal physician.
Included in this group are motor neuron disease (amyotrophic lateral sclerosis), myasthenia gravis, the muscular dystrophies, and the various inherited, metabolic, drug�induced, endocrine, infectious and other inflammatory myopathies.
The muscle biopsy is a reasonable next step. You may also want to consider an EMG. Other considerations would be a rheumatology consult if the muscle biopsy is not revealing.
Other lab tests to consider are aldolase, lactate dehydrogenase, and the aminotransferase levels.
I am not familiar with the PMCR/AKCR abbreviations - it is possible that they are different terms from what I am familiar with.
Bibliography:
Miller. Clinical manifestations and diagnosis of adult dermatomyositis and polymyositis. UptoDate, 2004.
Member Comments (1)
by kevinmd, Apr 07, 2004 12:00AM
To: Misc.
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