Lyme disease - early disseminated

Early disseminated or secondary Lyme disease is an inflammatory disease caused by the bacterium Borrelia burgdorferi.

See also:

• Lyme disease
• Lyme disease - chronic persistent
• Lyme disease - primary

Lyme disease - secondary or stage 2; Stage 2 Lyme disease

Lyme disease is transmitted through the bite of an infected tick. Secondary Lyme disease develops within days to months after the tick bite, when the infection spreads via the lymph system or bloodstream.

Lyme disease can affect the central nervous system and cardiac system. Symptoms can come and go and may disappear after days, weeks, or months.

Symptoms include:

• Blurred vision
• Fainting
• Fatigue
• General discomfort, uneasiness, or ill feeling (malaise)
• Headache
• Heart palpitations
• Joint inflammation in the knees and other large joints
• Lethargy
• Muscle pains
• Stiff neck

Other symptoms that can occur with this disease:

• Abnormal sensitivity to light
• Confusion
• Decreased consciousness
• Drooping eyelids
• Dysfunctional movement
• Facial paralysis (also called Bell's palsy)
• Hallucinations
• Loss of muscle function and feeling
• Nausea and vomiting
• Numbness and tingling
• Speech impairment

A physical examination may show signs of neurological problems or heart involvement.

Tests that may be done include:

• Chest x-ray
• ECG
• ELISA test to screen for substances specific to the infection
• Examination of cerebrospinal (CSF) fluid
• Western blot to confirm the presence of antibodies to Borrelia burgdorferi

The objective of treatment is to get rid of the infection with antibiotics. Antibiotics given through a vein (intravenous) are sometimes needed to cure the infection.

Getting diagnosed early and treating Lyme disease with antibiotics are the most effective ways to prevent secondary Lyme disease.

Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, et al. The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2006;43:1089-1134.