
Progressive multifocal leukoencephalopathy (PML) is a rare disorder that damages the material (myelin) that covers and protects nerves in the white matter of the brain.
The JC virus (JCV) causes PML. This virus is found in a lot of people, but usually does not cause symptoms. However, it triggers PML in people who have poor immune function (immunocompromised).
The disease occurs in 4% of adults with AIDS.
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