Welcome to our community! Patti you accidently posted your question on a thread that somehow got pulle up from 2006...I have a bit of advice in my opinion Im not a fan or premarine( you know its made from a mares urine right) bio identical hormones are different..most who use hormones prefere them ask your dr his opinion of Vivelle , its an estrogen patch easy to use its known to help w hot flashes night sweates and moodiness in particular. Black Cosch does help most not all and the doses can vary I am not qualified to tell you how much is safe to take. good luck please dont stop until you find the help you deserve there are soooo many options, its just finding the right one.
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