Just a quick note to say hi! dear sherri...i too have pbc. diagnosed about 7 years ago. i go to mayos and they have me on urso 250 at nite. urso 500 x 2 at nite, imuran 50 mg and prednisone 20 mg.....i also take herbs from goutwell.com for the liver and from hnmrc.net for pbc, chronic hep and cholestasis and hyperlipidemia. and i use oxygen sticks in my water. they have herbs for itching at hnmrc.net also. usually i do well...i am hoping to avoid a liver transplant. my total bilirubin has been a 10 before and now is normal. only have ast and alk phos high right now....i wish you all the luck in the world and many blessings!