I've had PVCs for 25 years and controlled pretty well with normal meds.No other health issues until I had increasing 24/7 PVCs with angina but clear caths.After my dx and nitro they went away.Then they reappeared 4years later.I had a sleep study done(not intentional)& found to have very frequent apnea.CPAP & they're gone.Address possible low O2 at night due to apnea.Joan.