Hi,
Thanks for taking the time to read this because I am seriously so scared by what is happening to me that it's ruining my life. I've been getting muscle twitching for about 16 months, and perceived weakness in my legs, particularly my right leg. I've also lost weight during this period (approx 24 lbs, mostly in the last 2 months). When I walk and my left leg is forward it feels tight/weak in my upper right thigh/groin which has affected my gait. It's almost like a minor limp but you might notice it if you were watching me walk. When sitting on a toilet seat or whenever there's pressure on the back of my leg (hamstring) I get pins and needless.
About 15 months ago i had an emg and ncv that was completely clean. It didn't pick up any fasciculations (but i wasn't twitching at the time of the EMG and NCV, not sure if this is significant). Then 12 months ago I had an MRI or the brain, spine, and cervical spine which was also normal. I've had 4 neuro exams (12, 10, 5 and 1 month ago), all of which were normal and the neurologist ensured me that I do not have anything neurological. However the numbness in my right leg has worsened and a second EMG and NCV (5 months ago) came back clean (again I wasn't twitching during the actual test) but they did find that the "right femoral cutaneous SNAP is absent, thus in keeping with right sided meralgia paraesthetica", which i've been told is essentially a trapped nerve in the right thigh. The report concluded that "nerve conduction studies of the upper limbs are within normal limits, with no evidence of entrapment syndrome or brachial plexopathy... EMG examination of the limb musculature reveals normal rest and volitional appearances, with no remarkable spontaneous activity, e.g. fasciculation potentials or neurogenic MUAPs seen to suggest neurononpathy/anterior horn cell dysfunction".
Like I said I wasn't twitching at the time though, if i was and it had picked up the fasciculations would it have meant something entirely different and more sinister? Also, since then (in the last 2 months) my left wrist had slimmed down and at times I get tingling in my ring finger and little finger as well as discomfort and tightness in my left arm (there's also tingling in the left elbow). When I say my wrist has slimmed down I mean the following (just to be clear), the muscle in my forearm (under-arm not on top) ends abruptly approx 2-3 inches before the wrist, this happens when I clench my fist. So it's a stright line from my wrist to that point, before the forearm muscles (under the arm if that makes sense) begins. On the right arm this isn't the case, there's a natural curve from the wrist to the forearm. My left wrist feels a little tight, like there's tape wrapped around it.
I've had a series of blood tests done (latest of which was approx 3 months ago) for muscle wasting, etc, and it was normal. About 10 months ago I also had blood tests done for Lupus, muscle wasting, uric acid, lymes disease, etc. Everything was normal except uric acid which was high (i already have gout but with medication those levels are normal now at 425) and low vitamin D (which is also normal now at 64). My ESR (for inflammation) is also now normal at 9, it was raised a number of months ago but don't know what the number was.
I've read things on the internet where people were diagnosed with minor issues and it turned out to be ALS or other MND and the anxiety is ruining my life. I'm simply constantly scared because my body doesn't feel right. Last week or so i've also noticed some unusual sensations in the left side of my face (like the skin is been stretched downwards). I've also had a burning sensation in my left forearm and when my left wrist or left thigh (left thigh hadn't had any symptoms until the last 2 weeks or so) gets cold or hot it takes longer for the temperature to come back into line with the rest of my body. Please help me, what's wrong with me? Do i have ALS, MND, PLS, MS or some other neurological disease?