Acne Caused By methotrexate

[neardark]

I have started to get severe acne on my chest, something I never had before, I suffer from Psoriais and take Methotrexate every week for that, the acne start a few months after I started taking methotrexate when my dose was increased to 17.5mg, everywhere I have asked people have said that methotrexate can cause acne, but when I asked my Derm if this would be the case, that the methotrexate was causing my chest acne, she said no, but looking at the side effects for methotrexate it says it can cause acne, so what's the truth, does mt derm even know what she is talking about? for the acne she has started me on Isotretinoin, this drug kind of worries me after looking at the side effects but will give it a go, am I right in thinking that if I stopped methotrexate then my immune system would build back up and fight the acne, clearing it? obviosuly my psoriasis will flare up too but that I can treat with a session of light treatment.

[loiloi]

Methotrexate can cause or worsen acne in some patients.
Isotretinoin is the most effective acne treatment available. It results in a long term remission from acne in over 80% of patients after just one course which usually lasts 16-24 weeks. It can cause unpleasant side effects but this must be balanced against the fact it is the "gold standard" treatment for acne and remission is usually complete and long-lasting.
Eloise.

[neardark]

Hi thanks for your reply, have you had personal experience with this drug and if so did you suffer any of the side effects, after looking at your profile I'm guessing you don't have any problems with acne, I'm just trying to get a picture of any side effects I can expect to get and know what ones I probably wont, Right now I am on 3rd day of taking 30mb a day, I do noticed my lips have dried up a bit but nothing bad and my eyes to seem to be a little nippy a couple of hours after taking it but it then goes.

[neardark]

Would I be also right in thinking if I was to stop taking Methotrexate then my immune system would kick back in and fight the Acne, my derm when I asked her said Methtrexate does not cause acne but everything I have seen on the net and people have spoke to say otherwise so dont know what to believe.