There are rumors that using a topical retinoid can make you break out for a few weeks or even months after beginning treatment. If I have been using Retin-A for the past year and I have overcome the initial break-out and then I switch to Differin, will I have another break-out period or will I circumvent that because it is also a retinoid?
Hi. Patients may experience an initial breakout (temporary worsening of acne) when using oral or topical retinoids.
Differin contains adapalene which is gentler and better tolerated than tretinoin (the active ingredient in Retin-A). I think it is unlikely that you will experience a breakout when changing to this medicine.
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