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228686 tn?1211554707

Interesting- the effect of tons of morphine during detox!!!

I thought I'd post this because it gives me hope that the way I'm doing this will work out (for others trying to cope with a similar situation).

For those who remember I've been on the LONGEST detox in this boards history. :)

I'm working on the theory that opaite neural receptors grow when taking drugs, so when you stop, they can take up to a year to die off (which leads to many of the problems with detox).

Well, I'd been holding at 1/2 mg of methadone because I'd been confusing Gal Bladder issues with detox issues (as you know, I just had mine taken out finally - thankfully). The end result is I've been at this dose level for at least six months (with many more months at similar levels).

When in the hospital, I was given TONS of morphine for about a week (intravenous).

Needless to say, I was a bit worried about the effect when I left the hospital and stopped taking it (all that morphine).

I'm happy to say I felt NO discernable side effects or withdrawals from the sudden rise and sudden drop a week later(likey 500% of my daily dose) which I'm taking as confirmation that  my assesment of the situation (in regard to neural receptors) is likely right.

hopefully this is a positive indication I've picked the correct course.
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402205 tn?1230481005
You and me both Mary!

Helpful - 0
306867 tn?1299249709
Kinda like fat cells , you gain weight, your fat cells increase.( I'm still working on killing the fat cells.) lol
Helpful - 0
228686 tn?1211554707
Ah, I mean if you took a dose NOW that is the same level you were taking six months ago (assuming your dose has decreased) it can kill you.
Helpful - 0
228686 tn?1211554707
Well, there's a number of theories here on how it works. I went with the theory that these receptors do gradually die off because;

A: There's a logic to it (If you take into affect how tolerance works, in both directions).

You build tolerance by growing receptors that need to be filled to feel the effects of the drugs...let alone normal.
If you stop for a significant period of time, a dose you'd taken six months ago could possibly kill you.
This would lend itself to the theory that receptors die off and grow.

B: It conveniently fits what I hope to be true. :)

My actual dosage in the hospital was some 5-10 mg's intravenous morphine every four hours for a week which did knock me for a loop at first (I believe by day 4 a balance was achieved due to the lack of methadone, which the weren't giving me).
On day 7 they gave me a 5 mg dose of methadone and kicked me out (complicated issue; gets into regulatory disputes over methadone maintenance between NY & NJ).

I cut that to 2.5 the next day and 1 the day after. On the third day, I went back on .5...and was presently surprised with the results.

It will be interesting to see what happens next. Now that these other physical issues are hopefully resolved, I can finally finish the whole thing up over the next three to six months.

There's quite a few doctors out there who disagree with the principle of this and state outright it DOESN'T work, yet it so far has.
Helpful - 0
Avatar universal
i aint even going to touch Savas and responsibities tonight!!!  But are you saying that you worked out the milli equivalents and that was the dose ratio/whatever? If so its very interesting. Not sure if those Mu things actually die off  -  I thought they just went to sleep.....but if they are asleep and you dont wake them up...........................keep thinking here Savas ----  eagle
Helpful - 0
228686 tn?1211554707
So far, I've been able to come done as far as I have with minimal to no "suffering". Which is important, if you've actually got..oh...responsibilities that you can't take time off from.

I don't know how many times I've heard people complain it didn't work out because they wre too uncomfortable to focus at work.
Helpful - 0
306867 tn?1299249709
So your saying a very long slow taper works best?  Hope so, thats what I'm doing with the Suboxone.
Helpful - 0
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