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True, for two years running I took up to 100 Vicodin per day (each pill with the equivalent of an extra-strength Tylenol in it) and through some work of the devil, I'm still walking around and my liver test three weeks ago was incomprehensibly normal. But I've been told by specialists that there are rare cases of people walking around that either naturally process Tylenol efficiently without appreciably damaging the liver, or, through years of progressively higher and higher doses, acquire a certain "resistance" to Tylenol's liver-toxic effects. I think I belong to the former category.
But if you're "the average joe," you don't enjoy that kind of safety margin, you need to heed the warnings on the bottles or from your pharmacist. I've most often heard that more than eight extra-strength Tylenol (generically called acetaminophen) has the potential, especially when there are other health factors involved, to cause irreversible liver damage leading to liver failure and death.
It's a lovely way to die, I hear. You get the news from your doctor that your liver has failed and you have a handful of days to live, allowing you to lie in a hospital bed and think about how you just threw your life away.
Of course, we're talking about maniacs like me who take ludicrous amounts of Vicodin, thus ingesting these aforementioned fatal doses of Tylenol. But, as I said, in my case, I have a deal with the devil that keeps me alive (I also haven't used Vicodin or Tylenol for several years, not wanting to test the limits of my infernal contract.)
As long as you don't exceed the maximum prescribed Vicodin dose, Bizziebe, you won't overdose on the Tylenol, so this message isn't really meant to alarm as much as educate you.
IMPORTANT: One recent, poorly publicized discovery, something you really should be mindful of regardless of whether you're doing one or 50 Vicodin per day:
Recent research has yielded what I understand to be pretty conclusive proof that mixing alcohol with Tylenol increases Tylenol's ability to damage the liver by a considerable margin. There is a well-documented story of a 30-ish man who downed three Tylenol with two beers and, as a result, died several days later of liver failure. The man had no previous history or either alcoholism or liver problems. Extreme example, I realize, but sobering tale, regardless!
This alcohol-tylenol "synergy of death" is on my mind from time to time because I know it's common practice for people to wash down Vicodins with beers or booze, either just to get a better buzz, or in an attempt at "stretching" their dwindling supply of Vics til he next refill becomes due.
Anyway, Bizziebe, especially since the MD on site took the time to address your concerns, I thought you were being ill served by not having the Tylenol-alcohol issue mentioned by him (Dr. Steve: educated, certainly, lazy, definitely).
Avoiding the problem, of course, is easy. Just don't drink with the Vics or anything with Tylenol (acetaminophen) in it. Tylenol, used properly, is still one of the safer, more effective over-the-counter painkillers around. I personally find enteric aspirin more effective (enteric ONLY, by the way, for your stomach's sake), but Tylenol, all in all, is still a good drug for minor pain and fever.
Hope this has helped without alarming you. From your earlier posts, it doesn't sound like you're doing anything dangerous with this stuff, but it's good to be aware of this stuff.
P.S. I repeated this same post in the next thread, but screwed up the paste job from Word, so I thought I'd try or a cleaner post.
Peace.
Well, I can now say that methadone is NOT like Darvon, at all. The family resemblance isn't even slight. Of course, I didn't trust this "maintenance" drug for pain relief for proper pain control and justified doubling the dose right off the bat. I was hurting pretty good and just for good measure, in case the methadone didn't help, I popped two Vicodin as well. Well, to my surprise, I actually got a little tipsy on 10 mgs. of methadone and 2 Vicodin. Moreso than the 8-10 10 mg. Vicodin I had been taking. So, I am sitting here wondering, is my tolerance really okay after all these years? I mean, some of the people that have come on here with meth.maintanence are starting out at 60mgs +! If I had popped that today, I would have been laid out, and I've been going through the Hydrocodone like water. So I'm at a bit of a loss here. Spook? Doc Dan? What gives with that? I was up in the 100-150 mgs. of Hydrocodone a day and got goofy on 10 mgs of methadone. tom, I know, you're probably wondering why I'm sharing this, but with your past curiosity about this and the why and why nots of doctors just prescribing it for pain relief instead of going to the "skid row" clinics, I thought you might be interested. So, I'm controlling my pain at a way low dose of methadone, and in the back of my head I'm thinking that I'm halfway to stopping it all when/if my pain issues get resolved. I'm rather stoked about the whole thing. My heart sunk when I didn't get put on the pure evil. Now, I know that it's in my best interest. Just as long as I don't go overboard with my monthly alotment now, that's the struggle. Anyway, there are doctors out there that are doing this. He is NOT a licensed methadone maintenance doctor either. He can only prescribe what he did for pain. It's too bad there's no standards in this country. Let me know what you think, or just read what I wrote, no big whoop. Take it easy, hope the programs still cooking along with you.
. . .as far as "Superlivers" are concerned, mine probably is up in the Hall Of Shame category, since after amnu episodes of abusing Vicodin/Tylenol w/Codeine/whatever containing Tylenol (usually by the handful), *then* going out and getting abysmally drunk -- I STILL have zero liver damage. Go figure. Again, to all reading, do not take this as license to be stupidly self-destructive, but I find the story of Tylenol and one beer a little (well, actually a lot) too extreme to be true without the presence of some severe underlying liver problem in the deceased (not that it makes any difference to the victim -- dead is still dead).
Peace,
Pelle
Also, I stand corrected -- the story referred to by Thomas of the 30-something (dead) man states that he had *two* beers, not one, with his three Tylenol. Again, my mistake.
Pelle
I'm immensely happy for you. No one deserves to languish in pain and I know you've been through a lot already.
Good luck to you, my friend,
Your friend,
Thomas.
1.Opioids(Hydrocodone) have no such Cardiotoxicity.in fact respiritory and gastrointestinal paralysis are the major short term and long term factors to concern oneself with.And even then the `Toxicity` is fully reversible.
2.It sounds to me that you suffer from Panick Disorder and have discovered that Opioids are a very effective anti-panick agent.
So now you can include panick attacks as a symptom of Opioid withdrawal.Typically they are not.
One thing that all Opioids have in Common is a resonable binding affinity for "Mu" Opioid receptors(PAIN) and stimulation of the Mesolimbic Dopaminergic VTA-Nucleus Accumbens reward circuit(EUPHORIA-unfortunate).
Methadone is goofing you out because it *(binds more tightly in relative global "Mu" receptor affinity to a sub-type) in the Mesencephalon area(brain stem) concerned with states of arousal and perception.
So it will make you spacey and drowsy and the Hydrocodone will make you "more" euphoric and alert and actived.
Methadone binds pretty strongly to gastrointestinal Opioid *receptors and is considered superior to morphine for stomach pain.
In fact I ONCE used so much Codeine SO often that instead of an Adrenalin RUSH resulting from fright I would get a Codeine RUSH,I have not bothered looking into the Neurophysiology behind this effect,but am not to surprised as Codeine is stimulant and will cause convulsions as per any stimulant in doses that are large(>300mg single oral dose).
Some Opioids are not very specific at all(Mu)receptor and are more Hallucinogenic than Analgesic,so they are not used much.
Methadone is ofen used for chronic pain sufferers in Australia,as it is considered qualitatively superior to Morphine for Chronic pain and can be given in a way that gives very stable blood levels,below is very approximate for single oral dose,nb Methadone will accumulate due to long half life.
10mg Methadone is equal to 30mg Morphine
30mg Morphine " " " 50mg Hydrocodone
and withdrawals. MMT is not about producing a high. Higher doses are needed some times to achieve this need. Pill addicts require doses in the 60-80 mg range to stop all cravings
and withdrawals. MMT is about being comfortable for 24 hours without cravings and withdrawals. Higher doses are needed to accomplish this feat. The high associated with methadone will rapidly disapate to produce a patient that functions without craving and withdrawals.
Dan...
"Benzos" are tranquilizers. The Benzodiazapine family. These include Librium, Valium, Xanax, Restoril, Ativan etc. All of these are closely related chemically. The relieve anxiety etc. Benzos also produce tolerance and dependence. At even moderate doses though, unlike opiates, acute (quick) withdrawal from benzos can be life threatening.
Sounds to me like you have your head on straight about both drugs and are taking care of any addiction and/or withdrawal problems on the front end by watching how many you take now. Very wise. Good luck, and be careful because they sneak up on you when you're not looking.
First reason is because with True Panick Disorder,the usual dosage required is 6mg(average)per day.
So the dose you take when you do take it for a "panick"? must be small <2mg or else it would knock you out(sleep),therefore I can only presume you take 1mg or 0.5mg,now it is not known to medical science (YET)that a dose of (Alprazolam)brand name "xanax" that small could stop a panick attack.
Next problem is between dose(interdose) anxiety,you see,even if you have been only using say 1.5mg per week average for 4 years it is unreasonable to miss a week without getting Withdrawal symptoms.
Conclusions,you do not have Panick Disorder Diagnosis.
Your Doctor does not know what Benzodiazepines are either.
You are not taking the medication as prescribed.
All of the above.
Well at least you know that Opioids are free of life threatening toxic effects(you know like tobacco,ie,CANCER).Although you certainly are far from knowing everthing their is to know about "Hydrocodone".
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Their actually is a Difference between Opioids and Opiates,"all Opiates are Opioids but not all Opioids are Opiates",does that clear it up?Clue:some come from Opium(Morphine Base),some are Synthetic,but all effect the Opioid Receptor System.
Give it away:Opiates come from the Opium Poppy.
Why not confuse things more and introduce the semisynthetic Opiates,ie Hydrocodone,also known as 14-hydroxy,7-8-dihydro,3-methyl,6-morphinone.
Basically they just grabbed some (god made-see Morphius)Morphine out of an opium poppy(natural) and then for some bizzare reason(honestly ,I do not know)have wacked on a hydroxy,2 hydrogens a methyl group and torn the hydrogen off the 6-position.
All this effort and the drug is just as if not more addictive than morphine.And no better an Analgesic.
The writing is on the wall for Oxycodone,next Hydrocodone can get the flick.
I think it is time SOME people woke up and smelled the poppies.
First reason is because with True Panick Disorder,the usual dosage required is 6mg(average)per day.
So the dose you take when you do take it for a "panick"? must be small <2mg or else it would knock you out(sleep),therefore I can only presume you take 1mg or 0.5mg,now it is not known to medical science (YET)that a dose of (Alprazolam)brand name "xanax" that small could stop a panick attack.
Next problem is between dose(interdose) anxiety,you see,even if you have been only using say 1.5mg per week average for 4 years it is unreasonable to miss a week without getting Withdrawal symptoms.
Conclusions,you do not have Panick Disorder Diagnosis.
Your Doctor does not know what Benzodiazepines are either.
You are not taking the medication as prescribed.
All of the above.
Well at least you know that Opioids are free of life threatening toxic effects(you know like tobacco,ie,CANCER).Although you certainly are far from knowing everthing their is to know about "Hydrocodone".
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Their actually is a Difference between Opioids and Opiates,"all Opiates are Opioids but not all Opioids are Opiates",does that clear it up?Clue:some come from Opium(Morphine Base),some are Synthetic,but all effect the Opioid Receptor System.
Give it away:Opiates come from the Opium Poppy.
Why not confuse things more and introduce the semisynthetic Opiates,ie Hydrocodone,also known as 14-hydroxy,7-8-dihydro,3-methyl,6-morphinone.
Basically they just grabbed some (god made-see Morphius)Morphine out of an opium poppy(natural) and then for some bizzare reason(honestly ,I do not know)have wacked on using heaps of dangerous chemicals: a hydroxy,2 hydrogens a methyl group and torn the hydrogen off the 6-position.
All this effort and the drug is just as if not more addictive than morphine.And no better an Analgesic.
The writing is on the wall for Oxycodone,next Hydrocodone can get the flick.
I think it is time SOME people woke up and smelled the poppies.
They do not smell like this $$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$
I know about the distorted horrific frightening sounds and fear of public places,learning to avoid the triggers,ie public, open places,public transport,public speaking,crowds,etc,will interfere with your daily life functioning to much and is the opposite to cognitive or behavioural therapy.This is when a Psychiatric nurse will accomply you into the situation causing fear and panick and stay by your side,as you feel better to handle it alone they will walk in front of you slightly and eventually when comfortable you can venture out on your own.Sometimes Panick disorder resembles social Phobia,this is when you feel watched in public,dislike eating in public or using public toilets etc,the social phobia seems to develop secondary to the inital onset of Panick disorder.
Hypochondria? and OCD?,in your case(fear of eating,because may be poisoned)although this is usually a withdrawal/rebound symptom of Xanax withdrawals,a type of delusional paranoia.So in this resect I highly suspect you are getting withdrawals from the xanax.
Zoloft is effective againced Panick attacks and is non addictive unlike xanax.Aurorix is good for Anticipatory aversion and panick attacks and non addictive,Xanax in daily dose of 6mg works fine,but I think one is rather spaced out and highly addicted and you may as well get drunk to achieve the same result.
I would go off xanax and Vicodin and once stable from withdrawals,commence an `ssri` like Zoloft or try an MAOI like aurorix(does not attenuate libido)and start on behaviour therapy,before things get beyond YOUR CONTROL.
Remember all addictive drugs will cause the opposite effects to that which they were originally intended durind withdrawal phase,this takes around 24hour on either xanax or Vicodin.
DAn...
I am also in end stage liver disease with Hep C and cirrohsis and need a liver asap. My wife has lung cancer that has not responded to any therapy yet. We are supposedly at death's door according to our doctors. I was supposed to be dead two years ago! We are both still very much alive and viable here so don't get too excited about the doctor's opinions and statistics.
God has the final say-so as to our fates in this life and no matter what we do...what will be, will be! We've had to go through all the various stages of fear, anger, denial, etc. to get where we are today...acceptance. Now we are able to go on with our lives with our heads held high. It's a feeling of hope, courage and dignity till "death do us part", amen. J.B.
China does not allow me much(any-well some,not complaining) freedom of speech either.I cannot help with the email problem as it IS my email address and even 20 mins before typing this.got an email from a friend in Australia and USA,possibly the problem is specific to this site,which means either the CIA NSA or FBI are responsible and are monitoring(blocking only to me,not reading subject matter) emails eminating from people posting to it?.
Maybe now I have said this they will back off,you know China and Australia get on quite well and USA is being non-complient with "global Warming" treaties drawn up in Japan.
I like Americans,its just that your system needs some fine tuning and course encouragement.
One world ,one day one system,Peace.
See my wisdom knows no boudaries and Politically,I think many decissions are "Unwise".
I have had a lot of experience with xanax and once I was sitting in a Doctors surgery in severe withdrawal,because I had Abused my supply and run out and the receptionist asked me if I wanted a glass of water,she was previous to this very rude and suggested the Doctor could not help me and I got bad vibes of her,not like she was`nt getting them of me either(xanax withdrawal)any way she got the water and I became suspicious that it was poisoned.
I have never had this type of thing happen to me before or ever again,it seemed to be a direct result of abrupt withdrawal from high dose xanax.
Now when one looks at the withdrawals symtoms in a Psychiatric Manual,well delusion,paranoia and Psychosis are to be expected from abrupt withdrawal from high doses.
Currently the accepted method of treatment for people with Paranoid delusions is Pschotherapy as it is complex in nature and the Psychiatrist needs to learn much about the patient and the evolution of the problem.
In my case it was a Neurochemical imbalance,supported by a reality state,that was the fact that the Receptionist was being rude and unfriendly and I was in Psychic HELL,so when she suddenly volunteered some water,it paved the way for the Paranoid delusion.
It is a fact that Xanax will make you feel better(as it stops ALL types of FEAR),but if you want a "cure" then you must explore the Pathogenisis of the illness.
The fear of eating may stem from an early repressed childhood memory whereby your mother accidently poisoned you with food and scolded you for not trusting her food after that.Who knows?
Our foods are already poisoned by hundreds of industrial chemicals,that work their way into the food chain.
You still have not stated the dose range you use,when you feel you need it,if it is a single 0.5mg tablet 2-3 days a week and you often miss weeks then you probably would not notice much.
Wthdrawal symtoms generally peek from xanax on day 5.
The 6mg dose I mentioned is only prescibed by Psychiatrists to people with refractive severe Panick Disorder.
Panick attacks always peak in around 20 minutes,so I am sure you can see the uselessness in taking the tablet upon having one.Altough they may last an entire day.
At the moment I am a Registered Drug Addict,meaning if I am in severe Physical Pain and see a doctor they ring the Health Dept and see if I am On the List and if they PRESUME I seek drugs because I am a drug addict,not for relief of pain.
Well they got that wrong last time I asked for Opioids,I WAS IN REAL BAD PAIN,but I could not point the finger at anybody,so I suffered and the suffering made me feel heaps better.
Besides,I have my morals and even when abusing and addicted,will not steel to procure drugs when money and supply runs out.
But I tell you this if I was in severe CHRONIC pain do you think for a moment Doctors ,DEA agents,or whatever could stop me from getting Opioids,No Frigging way,I can make my own,shift to Amsterdam,armed holdup a Pharmacy,etc,etc-you corner an injured animal(Human) and you watch you back,because in such a situation death is not a fear IT IS A RELIEF,what would I have to lose????????/pain?.
I receive email from all over the world,only people that cannot get through are Cindi and you,do you have anything in common,like have you ever been incarcerated for a drug offences or put on a FEDERAL data base of Drug addicts?.
For example I can never work for the Government while on the Register(and possibly never ever,as I do not believe they DESTROY the records),I was put on the Register of drug addicts when I went on MMT.According to a phone conversation I had with the `head` of the WA health dept my name will be dropped from the register 4 years after going off Methadone,that was 2 years ago,so officially I am still a drug addict for another 2 years(whoopy do-dah),even though I am not a drug addict and I only use drugs recreationally now and have not had any drug for about 6 days or so and feel completely normal,although I was drinking a bottle of beer everynight and I stopped that 2 nights ago and was very cranky yesterday and today,but the depression has lifted,so I have had nothing for 2 day,ie no chemicals and I feel GREAT,therefore I must conclude that being a drug addict is a good thing,well according to the Governent,otherwise I would be a winging drug addict asking for help would`nt I?.Or would I.
I am not saying(admitting) that I -<or--the Australian Govt has access to USA FED or State registers but I do believe? they exist.
I do not think that is the reason for the email diversion,but you must have some understanding of the nature of the ($*SYSTEM/s).
It is not perfect but it is all we have got and hopefully we will all improve upon it over generations.
A typical tablet contains somthing like this:
Zinc amino acid chelate 75mg
Magnesium amino acis chelate 37.5mg
Vitamin B6 10mg
Manganese amino acid chelate 10mg
Viatmin A (1000I.U.) 300mcg
Grading your habit on a scale of 1-10 (1 being occasional use and 10 being long term methadone at 100 plus mg's a day) you should take the following amount for a period of one month then slowly reduce to a daily amount of 2-3 per day.
Habit scale/size - Number of tablets per day for a month
10 10
9 9
8 8
7 7
6 6
5 5
4 4
3 3
2 3
1 2
0 2
You will notice that I recommend you never go below 2 per day. This is because zinc/mag depletion was your original problem so you should give yourself an ongoing supplement to make sure it does not happen again. I now take 2-3 per day to maintain my health. I have had no failures with this treatment (everyone OK after less than a month) and have treated addictions (including my own) as varied as methadone and cigarettes. The cigarrete smoker reduced from 2 packs per day to just 5 cigarettes per day in a week without any discomfort. If you suffer any kind of 'hang out' just increase the zinc/mag dosage and give it a liitle longer to take effect (a week or so). Don't beleive all the bullshit about drug addiction you have heard - it's all **** - this is the real deal. The drugs themselves are not actually addictive but they do leach all the zinc/mag out of your body by increasing the metabolism of them creating a shortage that gets worse the longer you use unless you replace them while you are using in which case you don't hang out when you stop - you just come straight - this is true beleive me I have tried it as have a few other people I know and none of us sufferred any hang out when we stopped.
DS