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I also am on Ultram and am now cutting down from 10 -50 mg tabs a day which my pharmacist informed me is already over the toxic limit. I only took two today and so far felt a little more depression and tingling feeling but when I took two tabs this morning the affects significantly went away. I do now have diahrea though I think is from the Ultram cutdown.
The tingling and depression and nearly psychotic thinking was from just starting Prednisone six days ago and that triggered increasing instability and tingling and brain zaps. I went off it today and the symptoms are disappearing.
So far no other effects from the Ultram cutdown. I'll keep you posted.
I also am on Ultram and am now cutting down from 10 -50 mg tabs a day which my pharmacist informed me is already over the toxic limit. I only took two today and so far felt a little more depression and tingling feeling but when I took two tabs this morning the affects significantly went away. I do now have diahrea though I think is from the Ultram cutdown.
The tingling and depression and nearly psychotic thinking was from just starting Prednisone six days ago and that triggered increasing instability and tingling and brain zaps. I went off it today and the symptoms are disappearing.
So far no other effects from the Ultram cutdown. I'll keep you posted.
I also am on Ultram and am now cutting down from 10 -50 mg tabs a day which my pharmacist informed me is already over the toxic limit. I only took two today and so far felt a little more depression and tingling feeling but when I took two tabs this morning the affects significantly went away. I do now have diahrea though I think is from the Ultram cutdown.
The tingling and depression and nearly psychotic thinking was from just starting Prednisone six days ago and that triggered increasing instability and tingling and brain zaps. I went off it today and the symptoms are disappearing.
So far no other effects from the Ultram cutdown. I'll keep you posted.
I also am on Ultram and am now cutting down from 10 -50 mg tabs a day which my pharmacist informed me is already over the toxic limit. I only took two today and so far felt a little more depression and tingling feeling but when I took two tabs this morning the affects significantly went away. I do now have diahrea though I think is from the Ultram cutdown.
The tingling and depression and nearly psychotic thinking was from just starting Prednisone six days ago and that triggered increasing instability and tingling and brain zaps. I went off it today and the symptoms are disappearing.
So far no other effects from the Ultram cutdown. I'll keep you posted.
People who have to live a life w/ a serious disease or injury,look at these medications as a God send. On the other hand if you were taking that much, HOW CAN YOU BLAME THE MANUFACTURER??? Even diabetics become addicted to their medications. To sum it all up: As long as people continue to blame doctors, manufacturers, etc. etc. etc. and everybody inbetween for their addictions....then patients needing pain medication will continue to struggle "in pain" to get physicians to prescribe what they so desperatly need to live some quality of a life. Belive me, Ive been there and back again. Its tuff.
Any time we put a pill in our mouths, as adults, we should take responsibility. Sometimes its just a necessary trade off and who's to blame????Anne
especially if an emergency were to take place and surgury would be required. Doctors will practicly give them away! (even though they do not work for pain). So everyone has a choice. Ultram is somewhat safe if taken correctly, and works well on pain. I dont belive in these types of lawsuits.......Cause the "good will end up suffering for the bad."
Thanks
Thanks
Sorry for the four posts, it was a computer glitch, not a brain glitch!
I have cut down to eight 50 mg tabs a day with no problems. The Prednisone was the problem.
The Klonopin is still the most effective for my particular problems.
Alcohol is the worst legal drug in the world and nobody seems to want to sue the companies for all the deaths, sicknesses, medical costs for rehab and it is clearly addictive with no mention of addictiveness on the bottles or cans. Only that it is dangerous for pregnant women.
One of my family members to whom I'm very close is suicidal. He first abused alcohol, now drugs. You know what his philosophy is
"I have no desire to be part of this world, sooo I will just continue to do drugs till it kills me"! Yeah its sad. I know. Here's a thought: Do you think that people are just suicidal; subconsciously, and this is why they drink and do drugs in lethal amounts, (knowing full well its killing them)or they just have a crappy outlook on life, or is it just a disease? I dont know I'm just really starting to explore this area.....Help me out. I know one thing for sure now, addiction; whichever form it comes in, affects every one of our live. Whether it be you or someone you know.........
Yes, I have a crappy attitude about life. I'm angry that we are not living in the Garden Of Eden! Enough said by this addict. J.B.
......And no I dont work for ultram....belive me somtimes i get p'od at the medicine too. I've been taking it for a couple of years now......If you read some of my post, the explanations are there.
.....Has anyone had withdrawals from Flexaryl (sp)????
Annie
Have a very good evening.
Annie (:
Will continue w/ it.
JB, I know this isnt a Pain site, but I realize that I will be on strong medication...I want to know about the warning signs of addiction. I feel really comfortable here. Given all this info, do you think that Neuropathy could be what I have?? Do you think flexaril would help you? Have you tried it? Annie
I thought I was a severe addict just taking 4percocet#5s per day!
Thank God I have not built up such a tolerance that I would have to take much more.
I do understand the basis of addiction though,as I used to get relief by taking only one Tylenol#3 and now....one of those have no effect whatsoever and I have to take two of them instead.
Getting this type of medication in my area is next to impossible!
It's tough when you finally find something that helps only to discover that you can't get a refill(which forces me to dr.shop)
I have a medicine cabinet that would impress any pharmacist,but the only pills in there that will provide relief for me have narcotics in them.
Your told to weigh the benefits of a drug with the risks involved before taking it,and that's what I did yet when trying to get a refill...I'm treated like a junky or something!
What do I do? Take the crappy anti-inflammatory medications that don't help and give me heartburn(which forces me to by more medicine for that?)
I think I have done well to have Reumathoid Arthritis,surgery for a pinched nerve in one elbow,the other elbow pending,and still able to work full time.
Perhaps I'm having myself a pitty party here,but why don't people understand that there are people in legit pain?
If they could come up with pain relief for me without drugs,then I would be first in line...but don't punish me for those that take pills just to get high!
I suffered for years, and it wasnt untill I literally began to fall apart at the seams that I began to get some relief. I know the feeling of being treated like an addict cause you want relief. My doctor shows disappointment all over his face when I come to the ofc. no matter how hard he tries to hide it. HE IS SCARED! The area I live in is pro-anti drug. lol What can we do??? Any suggestions.
I was in college at the time of this mva. My dream is to one day go back into the legal field, and go before the legislature and tell my story and that of others. This is of course a dream, because I am dealing w/ a lot of health issues right now.
Please let me know - i know i do need help and want to cut down. im back at work now and cant be on these - at times i feel dizzy and a bit sicky - not surprising though as im taking silly amounts. The gp has no idea -i get 300 tablets each 2 weeks - it should be every month - so far they havent said anything to me. I know they will soon though - and god knows what ill do then - i couldnt just come off or even cut down quickly - i need to do it slowly -even my family has no clue about how many i take . I have pictures of me dying of an overdose - not intentional -and it scares me alot - i dont want to die - im happy in life - have a husband and 3 kids.
If anyone knows the real dangers please let me know asap - thanks.
I go in next week for more tests and evaluations for this pain issue. Once, I asked my doctor for Ultram and he said he didn't prescibe it and thought it unwise for recovering addicts to take. That's all I know about Ultram. I surely have heard a lot of scarey things about it on this forum though. Personally, I'd rather take something that tried and true if you know what I mean? J.B.
Thanks!
I don't know why my doctor is against the drug. He just gave me a startled look like I had suddenly caught his attention. You've seen the "startled doctor look", haven't you? Well anyway, I'm trying to stay on his good side because he's the best doctor I've ever had and I don't want to rock the boat. BTW, he was in the nursing profession before becoming an MD.
Hope your day is going well! J.B.
Tom:.....I did the deal w/ the meds and water. Worked great, but was terrible going down. Thats why I will just try to get my doctor to give me something w/ less APAP. I've taken 45 tabs in 2 weeks.....Do you think I'm taking to much. As I told jb above...I dont know where to go from here. Its a dam shame you gotta go through this ****......Sometimes, I just feel like dealing w/ the pain. I should have been candid w/ my doc when I was there, and now I can kick myself. He didnt give me a course of treatment....sooo now I dont know what to do. I dont want to ruin this relationship, cause my pain WILL get worse over the next several months.
I wasnt that concerned about my internal organs till visiting here.
I discussed your dilemma with tom. He said that 45 tabs in two weeks amounts to 3 or so a day. This is not enough Tylenol to threaten your liver unless you have some aspect of liver disease. Do you? If not, then 3 Vics or Lortabs per day is nothing to worry about at all! The only way you could make this a liver-threatening practice is if you drank alcohol with your pain relievers. Tom recommends you abstain from all alcoholic beverages or medicines while using Tylenol. If you do this, don't trouble yourself a bit about your current Tylenol intake. You're well within the safe-use range for Tylenol products. When you start taking a dozen or more Vicodin per day, then you can be concerned about your liver!
As far as the "too soon" stuff with insurance, what's happening is, your doctor's instructions, say, 1 every 4 hrs as needed, are programmed into your rx record. The computer just does the math, and kicks it back if it thinks you are asking for them too soon. No big deal. I use a privately owned pharmacy run by two pharmacists I've known for 20 years. If the insurance says no, I tell them, "Make it for cash." They don't even ask anymore, they know the deal. And I simply pay for the privilege of refilling it before the insurance will pay. It costs more, but it gives me piece of mind knowing that I can pretty much get my refills when I want them, as long as I'm willing to pay the full cost of the rx. Chain pharmacies like Walgrens or Sav-on or Rite Aid, very from place to place. Some will refill early for cash, but most of the "new style" pharmacies play it buy the book and cheerfully tell you no with that plastic smile on their face.
See if you can find a mom-and-pop pharmacy where you simply call in the refill and say "that will be for cash, no need to run it through the insurance." It all depends on what kind of pharmacist you get. Most of the rosy-cheeked Asian pharmacists at the new chains just go by the book and that's that.
Ps....Pat, ask Tom how the tapering is going?? Hope he's ok.
He wanted me to relay to you the following:
"Addiction comes from deep inside the reptilian brain that lies at the core of our beings, the oldest, most entrenched and unquestionalby most powerful source of wants, needs and the impulses to satisfy those wants and needs. The cerebrum is lucky to even be consulted. The best it can hope for is a generous tip at the end of the evening.
No, mt only hope is one of the opiate agonist (MMT/LAAM) therapies, or treatment with a mixed agonist/antagonist drug such as buprenorphine. Before consigning myself to methadone, clearly the easiest route at this point, I would like to try detoxing with buprenorphine in a private, dignified doctor/patient relationship setting.
Click on this link for the complete picture of buprenorphine's impendng arrival in California doctors offices.
http://www.csam-asam.org/index.htm
If bup fails, that is, if I cannot finally taper off with bup and coax my own brain to start producing natural endorphins, then I will accept the finality of MMT and thank god (and Dan) for it.
I hope this has answered your questions. If you would like to research specific prescription drugs and the nomenclature that comes with them, click here:
www.rxlist.com.
Bookmark this site (make it a Favorite in your browser).
Never settle for the tid bits your doctor gives you about the drugs he's prescribing to you.
Annie, Knowledge is power. Knowledge is light and joy and the matrix of eternity enfolding, consuming and reusing you for its own pleasure. Live on and never stop questioning and wondering. We are the eyes of god gazing at our own reflection.
I belive my path will; however treacherous at times, lead me to my purpose. Sometimes man's will supercedes, but don't ever loose hope or faith! I would like to say much more, but I've been neglecting my work. I feel drawn here for some reason. Anyway, you have probably heard enough of this to last a lifetime.
I wish I had the time to increase my knowledge, which the demands of my life prohibit, but you are correct in what you say. I'm a little confused about the "God" part in your passage. Pleas explain. I know, duh. I'm just a "grasshopper," eager to learn. lol Hang in there.
Annie, I was only up to four Lorcet per day and found it necessary to quit. I started to take two doses at a time instead of one by "saving" the first dose and adding it to the second dose. That way I felt like I was really doing something. The truth is that my tolerence was building and needed more weekly. I began pill counting and playing games with them in short. The point is, if you think you have a problem then you do have a problem. With almost three weeks of being clean, I still can't be assured that I won't try opiates again. The whole thing is like a cycle that I can't get off of. Like the movie Groundhog Day! Today, I want to use really badly due to pain and fatigue and all the other **** in my life. Maybe I will and maybe I won't.... One minute at a time right now! We have liquor and benzos in the house and all it would take is just one dose of these and I think that I would cave in. Gotta get out of here, now. J.B.
I'll pray for you.
I have an update....Wasn't sure where to post it. This seems like a good place. I had a terrible night. Very severe pain. I'm sure yall gathered that something was wrong w/ me in my last posts'. My ortho now thinks I have sciatic (sp?) nerve damage. Can not have the test(mri) done because of the implant. Soooo guess what. Since its loose anyway, we will remove it next week. I'm scared. I wanted to wait, but I'm just putting off the inevitable. I will post during this time to keep up w/ my "new" friends. I've received (like you jb) sooo much support from this site. Came here for knowledge and left w/ friendships.
Keep me in your thoughts, and I will be in touch.
Sincerely,
Annie
Ps.....he has given me something for pain (can u belive it) Oxycodone...5/500....1 every 4-6 hours. Not helping much. Guess Ive already built up tolerance to meds.
k.i.t.
Annie
I'm dreading going to my next doctor's appt on Wednesday. He has been talking about draining my abdomen of fluid. I have ascities and have accumulated a lot of water lately. This is caused by liver problems. I just hope that I don't have to suffer much with this procedure. I heard that it can be very painful and Demerol will be administered beforehand. It's the unknown part that scares the hell out of me. I think that you know how I feel right now with all you've been through, Annie.
Take care and have a great weekend! J.B.
Hope you are okay. J.B.
any one know of any over the counter drugs that will ease this trasition .... any help would be appretiated
In the past, I've used OTC meds like Benedryl, Aleve and Dramamine. If you have the runs, try Immodium or Donnagel. Some people have found relief using herbal stuff like valerian root and ginger for nausea. I'd stay away from alcohol because it can make things even worse than they are now. Dr, Steve recommended a drug called Trazdone in his post up above.
Personally, I would talk with my doctor first about this problem before continuing with the Ultram. J.B.
i have nerve damage to my knee and lo and behold it is coming back with a vengence...now im in pain and STILL going through withdrawls wich does not make for a nice person...ive tried tylenol.. tylenol 3 {makes me sleepy} lortab just plain makes me sick to my stomach ultram as bad as it is ..is really the only thing that work's so what am i supposed to do?live in pain and be miserable or be an addict and be able to go to work and live a somewhat pain free life im still off ultram and it hurt's it sucks i feel so godamn sick ive already missed a day of work
any meds that any one knows about that works and doesnt turn your guts inside out id' love to know thanx....bill
Did you ever ask your doctor about this problem yet? J.B.
by
Dayer P, Desmeules J, Collart L
Service de Pharmacologie Clinique
et Consultation de la Douleur,
Hopital Cantonal Universitaire, Geneve, Suisse.
Drugs 1997; 53 Suppl 2:18-24
ABSTRACT
()-Tramadol is a synthetic analogue of codeine. It is a central analgesic with a low affinity for opioid receptors. Its selectivity for mu receptors has recently been demonstrated, and the M1 metabolite of tramadol, produced by liver O-demethylation, shows a higher affinity for opioid receptors than the parent drug. The rate of production of this M1 derivative (O-demethyl tramadol), is influenced by a polymorphic isoenzyme of the debrisoquine-type, cytochrome P450 2D6 (CYP2D6). Nevertheless, this affinity for mu receptors of the CNS remains low, being 6000 times lower than that of morphine. Moreover, and in contrast to other opioids, the analgesic action of tramadol is only partially inhibited by the opioid antagonist naloxone, which suggests the existence of another mechanism of action. This was demonstrated by the discovery of a monoaminergic activity that inhibits noradrenaline (norepinephrine) and serotonin (5-hydroxytryptamine; 5-HT) reuptake, making a significant contribution to the analgesic action by blocking nociceptive impulses at the spinal level. ()-Tramadol is a racemic mixture of 2 enantiomers, each one displaying differing affinities for various receptors. ()-Tramadol is a selective agonist of mu receptors and preferentially inhibits serotonin reuptake, whereas (-)-tramadol mainly inhibits noradrenaline reuptake. The action of these 2 enantiomers is both complementary and synergistic and results in the analgesic effect of ()-tramadol. After oral administration, tramadol demonstrates 68% bioavailability, with peak serum concentrations reached within 2 hours. The elimination kinetics can be described as 2-compartmental, with a half-life of 5.1 hours for tramadol and 9 hours for the M1 derivative after a single oral dose of 100mg. This explains the approximately 2-fold accumulation of the parent drug and its M1 derivative that is observed during multiple dose treatment with tramadol. The recommended daily dose of tramadol is between 50 and 100mg every 4 to 6 hours, with a maximum dose of 400 mg/day; the duration of the analgesic effect after a single oral dose of tramadol 100mg is about 6 hours. Adverse effects, and nausea in particular, are dose-dependent and therefore considerably more likely to appear if the loading dose is high. The reduction of this dose during the first days of treatment is an important factor in improving tolerability. Other adverse effects are generally similar to those of opioids, although they are usually less severe, and can include respiratory depression, dysphoria and constipation. Tramadol can be administered concomitantly with other analgesics, particularly those with peripheral action, while drugs that depress CNS function may enhance the sedative effect of tramadol. Tramadol should not be administered to patients receiving monoamine oxidase inhibitors, and administration with tricyclic antidepressant drugs should also be avoided. Tramadol has pharmacodynamic and pharmacokinetic properties that are highly unlikely to lead to dependence. This was confirmed by various controlled studies and postmarketing surveillance studies, which reported an extremely small number of patients developing tolerance or instances of tramadol abuse. Tramadol is a central acting analgesic which has been shown to be effective and well tolerated, and likely to be of value for treating several pain conditions (step II of the World Health Organization ladder) where treatment with strong opioids is not required
How about this one"Parnate is a non-hydrazine MAOI"is that descriptive?,like saying apples are a non-orange fruit,why the deception?because the Germans invented Tranycypromine(Parnate)as one of a series of Amphetamine analogues.
What about the brilliant Scientist who though that Heroin was a non addicting substitute(cure in those days)for morphine dependence.Or have TRIALS of drugs improved somewhat since then?.
Besides it is not Opioid receptors that make Opioids addictive and Euphoric>it is their effect (indirect)upon dopaminergic neurons in the Ventral Tegmental Area of the mesencephalon(midbrain),even Xanax exerts effects their.
Kappa receptors in the CA3 field of the hippocampus contribute to reward seeking,etc,etc.
If the drug companies think they can pull the wool over my eyes,I will fight to the death,take me on,I did not study 8 hours a day for 23 years for nothing,if I leave a mark upon this earth that in anyway helps humanity,it will be by exposing such unscrupulous behaviour.I mean do they really think that by avoiding the "mu" receptor they have made a non-Opioid,non-Addictive drug?.No sorry ULTRAM is addictive and causes Euphoria.
also, what sort of permanant (if any) physical problems and/or damage am i facing after over a year's addiction to Ultram?
Good luck; For anyone who hasn't tried it, my advice would be not to if you have any tendencies toward addictions of any kind.
Please feel free to contact me at ***@****
I was prescribed Ultram for a migraine headache in 1999. It was the only medication my doctor would prescribe for me due to the addition problems and rebound headaches caused by such drugs as Vicodin or Tyl.#3. I didn't care as long as I got rid of the headache. I was graduating the following day and needed help. I took two and the headache was gone in two hours after almost eight hours of pain. Now, they did leave me feeling bad but the headache was gone. I moved several months later and another doctor continued to prescribe them for me to keep for my headaches. I take them when I have a headache, sometimes they work and other times they don't. I have taken them off and on for the past two years. I have never taken more than two in one day, however, I have taken one several days in a row for several weeks. Usually with no problems after stopping. I do realize that I don't take a large dose, but I do feel some withdrawal from them when I stop. I feel Ultram is a good medication, just like many of them on the market. We shouldn't blame the doctors or the manufactures...we have only ourselves to blame for abuse. I know when I get a prescription for any drug that there is a potential risk of addition. I have never had problems with drugs or alcohol but I know personally I could have problems. Any medication over the counter or prescription can become addictive or dependent.
I was prescribed Ultram for a migraine headache in 1999. It was the only medication my doctor would prescribe for me due to the addition problems and rebound headaches caused by such drugs as Vicodin or Tyl.#3. I didn't care as long as I got rid of the headache. I was graduating the following day and needed help. I took two and the headache was gone in two hours after almost eight hours of pain. Now, they did leave me feeling bad but the headache was gone. I moved several months later and another doctor continued to prescribe them for me to keep for my headaches. I take them when I have a headache, sometimes they work and other times they don't. I have taken them off and on for the past two years. I have never taken more than two in one day, however, I have taken one several days in a row for several weeks. Usually with no problems after stopping. I do realize that I don't take a large dose, but I do feel some withdrawal from them when I stop. I feel Ultram is a good medication, just like many of them on the market. We shouldn't blame the doctors or the manufactures...we have only ourselves to blame for abuse. I know when I get a prescription for any drug that there is a potential risk of addition. I have never had problems with drugs or alcohol but I know personally I could have problems. Any medication over the counter or prescription can become addictive or dependent.
I have battled depression since the age of 12 and I am now 35. Last year I tried Ultram for a headache and unexpectedly felt my depression at the time lift and disappear completely for the rest of the day. A year later and many more Ultram tabs later I firmly believe in it's anti-depressant properties ( research show's that it also works to inhibit the reuptake of noradrenaline and serotonin as well as stimulating the opiate receptors) .I am also aware of it's addictive potential being a doctor myself and underwent a trial withdrawal 3 months ago reducing the dose from 6 a day to 4 a day for 2 weeks then 2 a day for 2 weeks then 1 a day for 2 weeks before stopping altogether. This slow withdrawal is needed because this drug similar to many other drug types leading to a withdrawal syndrome if stopped in a cold-turkey fashion. SLOW withdrawal is the key if you really want to stop.
Cheers Tom
NEW thread to this Forum I have decided to set up one. http://deadserious.planethosting.com/discuss
Please spread the word. I know we can continue to help and encourage one another.
If there is a forum topic any one would like covered just let me know.
Experiences with Oxycontin , Vicodin , etc..