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pain

by kiran naz, Mar 23, 2001 12:00AM
please answer my question i am a smoker and am suffering from phlemgh (mucus) in my lungs this only happens in the morning after i wake up, there is a shooting pain at the back of my head, shoulder blades, and lower back, these were the early symptoms, now the pain has gone to my knees, i am in great pain and the doctors don't know what it is , my blood tests are clear,

please diognose my problem as i really want to find out
Member Comments (33)

by spook, Mar 23, 2001 12:00AM
To: Kiran
I would be looking for a most probably(hopefully) Benign tumor pressing againced nerves that are capable of referring pain to the regions you mention,
Only problem is it must be located in the Cervical region C1 to C8 these innervate the back of the head(could it have spread from the throat?-smoking!),neck,shoulders,arms and hands but not legs or knees.the S1 or sacral region innervates or could cause pain in that area,I have looked at Dermatomes and cannot see a connection,so apparently the knee pain is of different pathology to the upper Cervical region.Could this indicate a progresion of the tumor down the spinal nerves,I doubt it.Get LATEST IMAGING TESTS DONE,
And please provide your complete medical history(all drugs you have or are currently using)what you eat ,exercise patterns ,lifestyle,Psychiatric Assesments,etc,etc,etc.Otherwise I am stumbling in the dark.Not that I cannot feel my away around,but you sound like you are ready to take OPioids and it is better ,well FAR better to fix the cause of the pain.

by chad, Mar 23, 2001 12:00AM
To: spook
Sounds to me he/she is ready to STOP SMOKING!!!!

by spook, Mar 23, 2001 12:00AM
To: Chad
My mother had to wait until (after 3 packets a day for 20 years)she had brocken ribs coughing and contracted lung cancer THEN SHE STOPPED.
see you soon Chad

by chad, Mar 23, 2001 12:00AM
To: spook
Spook what does that mean?  It's good people are trying to get help and I wish them all the luck in the world, god bless them, but if I had the trouble this person's having I wouldn't be sitting in my house/job on the internet looking for answers, I'd be at a clinic somewhere demanding tests on my body. If they didn't find anything, I would keep going on and on until I did find out what was wrong with me.  Some people just have a hard time breaking bad habits and Opiates are not the answer to everything, sometimes you have to go to the source of the problem and eliminate it, that's all I'm saying.  It doesn't mean they still don't need to stop smoking.  I know all about cancer.  I too have witnessed loved ones loose their battle with this terrible disease.  Sorry to hear about your mother, that's tragic for someone to go through. Just remember spook, other people have things to teach and storys to share as well.  Take Care
ChadB

by chad, Mar 23, 2001 12:00AM
To: spook
If I took that the wrong way, I'm terribly sorry.

by spook, Mar 23, 2001 12:00AM
To: Chad
Everything is cool,I agree with what you and most people would do,to solve medical problems,I am not really sure why I mentioned my mothers experience,must be some reason?
Kirin really needs to explain her whole pedicament more.before any usefull advise can be dispensed.
it does not seem to be an addiction problem.

by chad, Mar 23, 2001 12:00AM
To: spook
No man, that's cool.  Maybe you need to talk more about your mother, it's good to express.  I know I would.  It's a very tough thing to go through.

by spook, Mar 23, 2001 12:00AM
To: Chad
That was 15 years ago,she is now an attorney and owns her own lawyers firm and is resonably healthy for a 63 year old.My problem with her is her total reluctance to relate to me emotionally.But that is her problem ,that is the way she treats nearly everybody,my father divorced her because of these weird Character disorders.I hope you did not think she was dead,actually I was told at the time she had 3 months to live so I know the feeling anyway.

by CHAD FROM PHILLY!!!, Mar 23, 2001 12:00AM
This is a post from below. I am sorry that I had to post it again but I am tired of writing a long reply just to find it erased. Sorry for busting in on your thread....


It is so nice to know that there are people out there who care. Today is day 14 without Oxycontin! Finally I am starting to come back to life. I am so damm excited to see what life is going to be like off of everything. Can I just make a statement? People like Tom and I think maybe JB use to tell me about NA. I was like man, that **** is just not me! Tell you what! I love going to these meeting nightly. My girlfriend and I have already met some nice people our age. I already got a sponcer and I am about to start working on the steps. I am so glad I gave myself a chance to get over this.

Dee,
Just remember you can get off of the oxy's. It's very scary but it can work. I went from 300mg a day straight into detox. I don't think anyone should try to detox at home. You will be in alot of pain and you will be tempted to take a 20. Give it a shot! You never know, you may like it.

Patrick,
Thanks for saying "wuzz uppp!" I look forward to hearing from you!

Everyone,
Did any of you see the NBC nightly news last night? They are talking about weaning everone down off the oxy's by October. They (perdue) are trying to fight it. They also said that no new patients will be issued oxycontin scripts. What the hell are all these people who really need this medication going to do?

Thanks for reading......If any of you would like to chat one-on-one you can e-mail me at ***@****
I look forward to hearing from you..............CHAD

by CHAD FROM PHILLY!!!, Mar 23, 2001 12:00AM
To: chad
Stop using my name god-dammit! I will come down there and set you on fire! Did you ever hear of that GAY BAND from the Baltimore area called LACHOZA? They really kick ass!!! Just because they dress in leather thongs doesn't make them a bad band. You just have to be comforatable enough with your own sexuality. During the show I hear they bring out a sheep and..........just go to one of there shows

THE ONLY TRUE CHAD!!!

PHILLY ALL THE WAY BABY!!! CHEESESTEAKS AND CRACK! NO OTHER CITY CAN TOUCH US!


just in case any of you are bothered by this post. my apoligies but I think some of us should lighten up a bit...

by The Dude, Mar 23, 2001 12:00AM
To: CHAD FROM PHILLY
We actually use a toothless goat on stage, he likes it when we tickle his scrotum.
WWW.LACHOZA.TV Baltimore MD.

by cindi, Mar 24, 2001 12:00AM
To: Spook
Your mom is very luck to have come through the lung cancer,  My mom was diagnosed with emphysema in 1989 and did not quit smoking until 95,  became progressively worse and I watched her struggle for every breath until she ended up on a ventilator and died 3 months ago  On Christmas day.  I don't know why I even posted this but I will struggle with this for the rest of my life,  Thank God you still have your mom and she is doing well.   Cindi

by cindi, Mar 24, 2001 12:00AM
To: TO CHAD FROM pHILLY
I missed the news last night,  I am concerned about the oxy's.  after years of intense pain my my husband's doc just worte him a script for oxy's.  Only ten mgs but they do help.  after many years of various meds this helps him and they are taking it off the market?  This **** is so unfair......take care cindi

by CHAD FROM PHILLY!!!, Mar 24, 2001 12:00AM
To: cindi
I just want everyone to know that I am only stateing what I saw. The show was broadcast on NBC at 6:30 eastern time. I'll try to sum it up as clear as I possibly can.........

The FDA is concerned about the abuse of the drug oxycontin
They are already sweeping the nation in an effort to bust doctors who freely write scripts and patients who obtain to many scripts.
Remember every script of a narcotic is recorded by the DEA. at least it is here in PA.
They said that if they can come to the conclusion that more people are abusing this drug than the one's who need it than they would consider taking it completly off the market!
Remember they can and do have the power to do this.
No new perscriptions are currently being issued untill October.
People who are currently on oxys have nothing to worry about until then.
They also stated that eventually (october) if the dessision is made by the FDA that they would wean the current patients off of the drug.
Purdue Pharm (makers of oxy's) are curantly fighting this...

Time will tell. Like I said. I'm not making this **** up.
sorry for my spelling........I am typing very quick!
Chad

by cindi, Mar 24, 2001 12:00AM
To: To Chad from Philly
Thanks for the info...I believe you, I have no reason to think your making anything up...but i am concerned about the oxy's being taken off the market, like you, I think about what happens to the people who need it.  thanks for the info   cindi

by spook, Mar 25, 2001 12:00AM
To: Cindy
Thankyou for sharing and caring,my mum is one tuff(tough)son?sorry daughter of a *****(a real Woman,no bullshit),your replies always give me warmth in an otherwise chemically warm world.God bless you.Actually if I live another 10 years I will obtain access to  3 million dollar trust account,but life without love is a sick JOKE.thank you again and please if I can help in any way pleae ask.

by spook, Mar 25, 2001 12:00AM
To: CHAD FROM PHILLY!!!
As a Neuropsychopharmacologist; I am Am not impressed(disgusted) with OXYCODONE,it comes on fast-(orally or snorted or IV)gives a heroin like rush,has no analgesic effects to surpass Morphine and represents the exploitation of Pharmaceutical companies to brain wash MD`s and Doctors(GP`s),that Codeine Derivatives are less ADDICITIVE than Morphine Analogues ie-,OXYMORPHONE,HEROIN,ETC,this is a scam and the DEA has every right to kick the Pharmaceutical companies Butts,but I am terribly sorry to those already ADDICTED who will suffer.As  nothing will change until government acknowedges that it is a Basic Human Moral RIGHT to get STONED.And you are the one who is going to suffer not the MANUFACTURERS.
Note.I found heroin much easier to get off than OXYCODONE!!!!!!!

by spook, Mar 25, 2001 12:00AM
To: Chad
Toothless goats,are a poor substitute for a loving women with dentures.

by cindi, Mar 25, 2001 12:00AM
To: SPOOK
Thank you for the nice comment above re: your mum.  My mom was a very strong person in her own right, she fought like hell as she was so afraid to leave behind her kids and her grandkids.  (Ok her cat to)  but in the end I had to assure her I would take care of everything,  how can i do that when I can't get past her death.  my days seem so dark and something is missing, the phone calls to my mom etc.  I guess time will help,  Luke, underneath all of your education and intellect, you are wonderful, compassionate, caring man, Not that education and intellect are bad things, they make for very interesting people, but I get the impression that love is very important to you.  you have made several remarks in other posts about how much you love women, and how love is so important to you etc.  I hope that you have some wonderful woman in your life that brings you nothing but happiness and if you don't then I hope you find her real soon..everyone deserves someone.   Love to all cindi

by Dee, Mar 25, 2001 12:00AM
To: Cindi
Cindi,
many times I have started to write to you only to delete it,
even now I find it very hard to continue with this post, I have read each post you have written about your mom, I have been waiting for it to get easier for me to be able to 'talk' about it but now realize that time will never come.I truly feel a 'connection'with you on this subject..first let me say, I'm sorry for the pain that you have felt and still feel, you see I, to lost my mom to emphysema in april of 1997 we had her wake on my Birthday..it never has gotten 'easier' for me, my mom was not your 'classic' emphysema patient, hers was a 'unique' case..for you to understand that, you would have to know the whole story..
I just wanted to let you know that I feel your pain, (literary)and if ever you want someone to talk to or someone to just listen to you,Iam here..maybe it's time for me to open this wound and let it heal..as much as possible I guess..my email is ***@**** if ever you feel the need...my thoughts are with you..
Dee-not deedee
PS
hopefully this post will not be deleted, please whoever is in charge of the posts, please give Cindi the chance to read this

by cindi, Mar 25, 2001 12:00AM
To: DEE
Thank you for the post, luckily I did get the chance to read it. I am very sorry for your loss.    To talk to someone who has lost a mom is such a relief, I wonder through my days aimlessly, I cry my self to sleep each night, I never imagined the pain could be so intense like my heart has ben ripped apart and is laying in the bottom of my stomach.  Anyway, if I keep on going my post will be deleted, so I will write to you.  You can always send some mail at ***@****.  I will be looking forward to hearing form you   thanks again  Love to all  cindi

by PS >>>>Annie, Mar 25, 2001 12:00AM
To: Dee and Cindi
.....I feel compelled to respond to you guys.  I have loss 2 people very close to me also.  2yrs ago my friend, 1yr ago my grandmother.  They both loss the battle to cancer.  I think of them often.  
I'm not sure if this will help, but here goes.  I can recall looking at my friend lying there at the wake.  I couldn't even cry...she looked so peaceful.  I remember thinking...all your suffering is over.  You are a winner.  Sounds a little weird, doesn't it???  When ever I'm down...I think of them.  They are totally at rest...I know this will never resolve the "loss" you feel, and you really miss them.  We are the ones who are truly suffering now.  Dealing w/ everyday life.  
Just try to see them as angels now.  This will comfort you.  I can recall times.....when I ask them, "are you w/ me??"  What do you think about this or what do you think about that???  I may seem a little crazy, but this offers some peace and comfort to me.  I guess what I'm trying to say is:  Don't think of the last minute you saw there faces...talk to them as though they are still w/ you.  This really  helps.  
annie
Ps....It may be wise....not to talk to them out-loud when people are around.  Just a little humor there. lol  Hope you feel better soon.

by cindi, Mar 25, 2001 12:00AM
To: Annie
Sometimes it is very hard to remember that I am not the only one dealing with the loss of someone we love.  Ever minute someone suffers through a loss such as this, JB lost a daughter, how does one get through that?  I know my loss is still "new" and in time my thoughts and bitterness will turn into good memories.  I try not to think of seeing her as sick as she was but the day before she died she begged me to help her, i told her I would but I let her down.  I talk to her all the time, I even yell sometimes as crazy as it sounds.  My dear Annie, you seem to always be here when I am down and on more than one occasion you have given me words of wisdom and encouragement, and for that I love you.    Thank you    love to all   cindi

by PS >>>>Annie, Mar 25, 2001 12:00AM
To: PAIN INFO. AND UPDATE
This is to all my forum friends that problems relating to intractable or chronic pain.

HOORAY!!!.....I think I may have located a doctor in my area.

Visit these sites:
MED-HELP.COM (different than this site)Helped in locating a dr.
***************************************************************
Dr.Fisher.org...more or less, an FYI site.

The widomaker.com/~skipb......Most of you know about already.

The MED-HELP site gave me the names of 2 doctors in my area that deal w/ arthritis aggressively.  Perseverance pays off.  I'm am trying not to get my hopes up though.  As soon as I am released from dr's care, I will contact them.

also, you may email ***@****, and be sure to include your zipcodes and surrounding areas.

Although this is an addiction message board, there are people who frequent here, such as myself, trying to understand addiction and long term effects of pain medication to treat chronic pain...to aid in making a decision on whether or not opiate treatment is right for them.  I posted this information w/ this in mind.

Annie

by PS >>>>Annie, Mar 25, 2001 12:00AM
To: Cindi
I'm so glad to have helped.  I can stand to see someone hurting, whether it be physical, emotional, or mental pain.  Your getting stronger though.  It will all work out in the long run.  You will see.

Love you too!

Annie

by cindi, Mar 26, 2001 12:00AM
To: Annie, jb,Spook, Patrick for Tom, Brighty
Ok guys, I needed to vent...A few weeks ago i had a mild (if there is a mild) case of pneumonia,  It cleard up and I was fine for a few days.  I ended up with a cold and cough again last week and last night I ended up in this God awful pain started in my chest, radiated down my arm and into my neck,  It hurt so bad I could hardly breath, I have had pain from pneumonia before but this was the worst it has ever been,  LORD!!! I thought it was the big one,anyway, it became worse overnight so i called off work and went to an immediate care place, my doc was not in today
they did blood work, a few breathing treatments and a chest x-ray, the pain was so intense i could not even lift my arm up for the x-ray...Ok to make a long story short, doc comes in and says, "ok little lady you have a pretty bad case of pneumonia, that's why you are having such a hard time breathing and have so much pain,  No **** sherlock, That's why I came in  he then proceeds to tell me he has ordered my an anitibiotic, not the kind I usually take for pneumonia, i tried to explain to him what i normally take and he didn't want to hear it,  then he gave me a script for what he said was a really strong pain pill,   ANAPROX  a lousy NSAID and absolutely no cough medicine.  Nothing, he wants me to cough.  ok coughing is intolerable because of the pain, couldn't he at least have given me somethig real for the pain?  I don't get it?  I called my doc's office when I got home and told them what he gave me, she did not really believe anything I told her and would not call my doc.  She acted like I was looking for drugs,  I told her if she didn't belive me to call the Er and have them fax over the reports,  I did manage to get an appointment to see my doc tomorrow.  The doc at the ER did say he wanted to have me admitted to the hospital but i protested that one, my husband is laid off again and our insurance is gone.  If I am that sick why did he not give me the anti biotic that usually helps, y didn't he give me something for the pain  Do we have to beg?  Seriously, do you guys think I am over reacting?  I just think that something is really wrong with this whole picture, a friend of mine c-section, her doc ordered her what he called a really strong pain med also,   Vioxx...  85 year old gramma,  Hip nailing done,  tylenol for pain, All  I want to do is lay down and sleep without all the pain and labored breathing.  Ok,  actually, I don't even know what the purpose to this post was, I just needed to vent, i am so tired of the shabby treatment and insensitive, uncaring people,  If this doc had been feeling like I do you can betyurass that he would do his own self medicating... I know how Annie was treated in the hospital,  this is pathetic.  The pain as so bad by this evening I ended up taking n Oxycontin from my husband,  they are only 10 mgs so i had to take more than that but they at least took the edge off, now if oxy's didn't help completely how the hell is anaprox going to do the trick  it never helped with menstrual cramps oxy didn't help completely because the pain was too bad I didn't get to it in time,i can't keep on with the oxy's because they belong to my husband and it is only a 2week supply and I don' want him to be shorted, his pain is chronic and constant.  sorry this post is so long but i get so upset about the undermedicating issue.  Take care and thanks for listening   Love you guys   cindi

by PS >>>>Annie, Mar 26, 2001 12:00AM
To: cindi
Cindi,

This will be frustrating, but give it a try.  Get copies (in hand) of all your records.  Make an appointment w/ another doctor.  Bring all these records.  Meanwhile, email ***@**** w/ your total story.  Make sure you don't leave out any details...ya know about these phobic doc's.  Then email the same story to ***@****.,AND send all local zip codes surrounding you.  Make sure you emphasize your condition and all the problems you've had, and possibly your husband, has had w/ doctors and their lack of compassion where you live.  We need to get the word out and pull out all of the stops.  If any thing you will get hooked up w/ a real doctor for the next time your in need, because you will probably be healed from the problems you have at present.  Another thing....log on to MED-Help.com (a different site than this one) and search for a doctor in your state....especially for your back.  You may need this in the future.  

I have found some great information from these sites.  I thought that I was living in the drug desert, but not so.  Those doctors are out there.  You just have to find them.  Hope you feel better soon.  I FEEL YOUR FRUSTRATION.....BIG TIME!

lOVE yA!
ANNIE

PS...If things don't turn out well for me .....I will email my story to all the major news stations(sometime in the near future).  I want the inhumane side to "The War on Drugs" to be shown.  If only I could get Tom/patrick to write my story for me......lol  He's a pro at writing.....this we know. lol

by Thomas02, Mar 27, 2001 12:00AM
To: Annie for tom
annie,
send me a rough draft or at last an outline of the points you want to make in your article/letter/essay. Define the audience (and where you think it might be puslished) and give me an estimate of how many words it needs to be. I would be glad to edit it and shape it for you, but the story and, more importantly, the passion or indignation behind the story has to come from you. I can structure it, trimming any fat and sharpeing its focus. We can also employ a few profesional writer's tricks to make it "punch" where it has to. If you have the goods, i.e., substantiating facts that stand srutiny, and the power of rightousness and indignation on you side, and we have a clear picture of who the audience is and how much room we have in the proposed pulication, we should be able to make a powerful statement that will not be easly dimissed. Give me the raw material; I will apply what I know about doing pursuasive writing to your message. We do it right - they won't know what hit them!! Remember: power, economy, truth and passion are what makes for powerful writing. Good luck,annie, my friend.

***@****

by cindi, Mar 27, 2001 12:00AM
To: Annie
Thanks Annie,  hope you're feeling better  Love ya  cindi

by spook, Mar 27, 2001 12:00AM
To: PHreaKS
Hydrocodone and Addiction [posted 8/14/98]

I was prescribed Hycodanä(Hydrocodone),it was much more habit forming than I expected it to be. Most of the time, I took 1 teaspoon. However, if the cough was extremely bad, I would take up to 3 teaspoons (15 mg). At this dose, I would receive extreme euphoria, much more than I've received from Codeine 30 mg). Ultimately, I became addicted to the Hydrocodone and I had to be detoxified with Methadone.I've been prescribed Codeine Phosphate 30 and 60 mg which certainly didn't cause nearly the quality and amount of euphoria that the hydrocodone caused.I have taken Percodan (oxycodone) and I certainly feel that the propensity for addiction from the hydrocodone is equivalent to the oxycodone.Hydrocodone is 8 times more potent by mouth than Codeine.
=====================================================================
Dihydromorphinone and Dihydrocodeinone from morphine and Codeine
=====================================================================
German Patents 607931, 617238 (both from 1935) and 623821 (1936), all
describing the rearrangement of morphine, codeine and ethylmorphine into
the corresponding dihydromorphinones. The first uses immense amounts of
platinum or palladium in acid solution to affect the rearrangement, the
second uses a lot less catalyst, and the last one uses alcohol as solvent,
in which the reaction proceeds without any acid added.

Translated from german by Rhodium. Thanks to Piglet for sending me copies
of the original patents.


Procedure for the Production of Dihydromorphinones

It is well known that morphine and its ethers, through treatment
with hydrogen gas in the presence of large amounts of noble metal catalysts
through heating the acid soln., can be transformed to the dihydrated keto
derivatives.
Surprisingly, it was now found that for this transformation to take
place, hydrogen is completely unnecessary, and that just heating the
acidified alkaloid solution with a larger amount of finely divided platinum
row metals, will suffice to affect the simultaneous dehydration/hydration
in good yields.
This success is particularly unexpected because it was not to be
foreseen that platinum metal not saturated with hydrogen is capable to use
the hydrogen originating from the dehydrogenation [of the 6-position]
almost quantitatively for the hydrogenation of the double bond [in the 7-8
position] of morphine or its analogs without the addition of excess
hydrogen from an external source.

Example 1:

300 grams of codeine free base was dissolved in 2000ml dilute HCl, and
after the addition of 150 grams finely divided palladium, the mixture was
heated under reflux for one hour. After the palladium was filtered off, the
acid filtrate was basified with NaOH solution. The base which separated was
recrystallized from alcohol. Yield of dihydrocodeinone 75-85%, mp 195°C.

Example 2:

5 grams of codeine hydrochloride was dissolved in 30 ml water, and
acidified with a little HCl, and after the addition of 4 grams platinum
black, the solution was refluxed for 5 hours. After workup as in example 1,
the yield was 65-75% of theory.

Example 3:

5 g of morphine HCl was dissolved in 50ml water, slightly acidified with
HCl, and 5 grams of platinum black was added and the solution refluxed for
4 hours. Workup as in example 1. Yield 2.5 grams dihydromorpinone.

Example 4:

To a solution of codeine hydrochloride, slightly acidified with HCl, 50 ml
of a 10% solution of colloidal platinum was added, and the solution was
refluxed for 3 hours. Workup as in example 1. Yield 3 g dihydrocodeinone.

Example 5:

6 grams codeine freebase was dissolved in a solution of 4 grams of tartaric
acid in 50 ml of water, and 6 grams palladium black was added. The solution
was refluxed for 1 hour and worked up as in example 1. Yield 75% of theory.

Example 6:

6 g codeine phosphate was dissolved in 30 ml water, and acidified with 5ml
dilute phosphoric acid. 4g of finely divided palladium was added, and the
solution was refluxed for one hour. Workup as in example 1. Yield 60-70%.


Example 7:

21 grams of codeine free base was dissolved in an excess of dilute sulfuric
acid, mixed with 16 grams palladium black and refluxed for one hour. After
workup as in example 1, the yield was 80-85% of theory.

==================================================
Procedure for the Production of Dihydromorphinones
==================================================

As in patent 607931, a method is decribed below for the production
of dihydromorphinones by rearrangement without the use of hydrogen, but
simply by heating the alkaloid in an acidic solution together with a
platinum catalyst.
While in patent 607931, relatively large amounts of platinum
catalyst is used, we have found that only a fraction of that amount is
needed, and sometimes with even better yields.

Example 1:

300g codeine freebase was dissolved in 2000ml dilute HCl Acid containing
25.0g of finely powdered palladium, then boiled under reflux for one hour.
The palladium was filtered off, and the filtrate basified with NaOH
solution. The precipitated base was recrystallized from alcohol. Yield
85-95% of dihydrocodeinone, mp 195°C.

Example 2:

5 grams of codeine hydrochloride was dissolved in 30ml water, and acifified
with a small amount of HCl, and after the addition of 0.5g of palladium
black, the mixture was refluxed for five hours, and worked up as in example
1. The yield was 70% of theoretical.

Example 3:

6 grams of codeine freebase was dissolved in 30ml water together with 4g of
tartaric acid, and 0.5g of palladium black was added. The mixture was
refluxed for one hour and worked up as in example 1. The yield was 75% of
theory.

Example 4:

6 grams of codeine phosphate was dissolved in 30ml water, and acidified
with 5ml dilute phosphoric acid, and after the addition of 0.5g of
palladium black, the solution was refluxed for an hour. After workup as in
example 1, 60-70% yield of dihydrocodeinone was isolated.

Example 5:

21 grams of codeine freebase was dissolved in an excess of dilute H2SO4,
and two grams of palladium black was added and the solution refluxed for
one hour. The yield was 90% of theory.

==================================================
Procedure for the Production of Dihydromorphinones
==================================================

As in patent 617238, a method is decribed below for the production
of dihydromorphinones without the addition of hydrogen gas.
While the rearrangement in patent 617238 is affected by the
presence of acids, we have now found that the reaction with morphine and
its ethers is taking place in an alcoholic solution in good yields without
the addition of any acid.

Example 1:

5 grams morphine was dissolved in 50 ml of alcohol and after the addition
of 0.5g of palladium black, the mixture was refluxed for 4 hours. After the
catalyst was filtered off and the solution concentrated, dihydromorphinone
crystallized. Yield 3 grams.

Example 2:

10 grams of codeine was dissolved in 100ml alcohol, and after the addition
of 0.5 grams palladium black the solution was refluxed for 4 hours. Workup
as in example 1. Yield 7 grams of dihydrocodeinone.

Notes

1. Finely divided platinum (later called Platinschwarz by Justus von Liebig and Platinmohr by Döbereiner - both meaning platinum black)
2. platinum black [METALLURGY] Black-colored, finely divided metallic platinum; soluble in aqua regia; used as a catalyst, as an absorbent for gases (hydrogen, oxygen), and for gas ignition.Also known as platinum Mohr.
3.Finely divided palladium, called palladium black, is used as a catalyst, a substance that causes or speeds up chemical changes. It is an important catalyst.



by PS >>>>Annie, Mar 27, 2001 12:00AM
To: Pat
Man.....Your awesome!.....I was really kidding.  I hate to ask you to do something like that.  If anything, it would be wonderful to see how this work of art unfolds.  I have stated strong points from my arguement throughout this forum.  All with meaning, fact, and passion.  Give me some time to get it all summed up.  This may take some time, cause I'm back to the grind again.  I also want to do some research on the internet...just to see where the best outlet might be.  
Also, I'll need to prepare myself....If this thing takes wings and flies...I'll need to get pass my shyness.  lol  Me shy??? Yep, you bet.  You wouldn't know it from my postings.  This has a way of working itself out though....when you have passion and purpose toward something.  HUM....I wonder if we could tie addiction treatments in there somewhere??? Ya know, since chronic pain patients do have to deal w/ this.  Now I'm just rambling away.....Oh think of the possibilities: of what a story like this could do???  I bet we could stir up a mess. lol  Think of the people that would come to the fore-front.  The more the merrier.....Hey maybe we could send this to congress, or to all our reps.  Let me know what you think.
Love ya!

Annie

by PS >>>>Annie, Mar 27, 2001 12:00AM
To: Pat/tom
I have another post for you under MANAGING PAIN WHEN ADDICTION HAS BEEN A PROBLEM.  Help!  lol

annie

by PS >>>>Annie, Mar 27, 2001 12:00AM
To: Pat/tom
I have another post for you under MANAGING PAIN WHEN ADDICTION HAS BEEN A PROBLEM.  Help!  lol

annie
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