Aa
when can i expect withdrawl to set in?
i quit subutex cold turkey four days ago. i was taking 24 to 32 mg a day (yes i know thats alot) i was on this dose for about six months. i still do not feel any different. no withdrawl symptoms or any discomfort whatsover. whats going on?
That's whati was explaining the second time I did because when u take 4 or 8 or however much the BA which is the bioavailability is not 100% I'm not sure what the BA of suboxone is but just for example say its 30% that means only 30% of the dose you take actually gets in your bloodstream and works not the whole 4mg or however much you take does that make more sense so if u take 8mg you won't actually get the ceiling at 4mg unless the BA is 50% or more. Does that make more sense
I have a question for abritt. When u say " ceiling" normally tht means tht once u get to tht dose it does nothing more. So say suboxone is 32 mg if i were to take 40mg it wouldn't do anything more than it would have done at 32mg. But at 4 mg i can take 4 more mg and it will continue to work more. My dose is 16 mg a day and sone days i take 8others i take 16 and u can feel the difference between the two. Im not arguing just what my dr said. Ur post was a little confusing thts all. And for the OP i woyld suggest a slow taper even if its a week of the lower dose then drop again for another week and so on bc the wd u are going to go thru is going to b VERYYYYYY bad!!! Id like to see u succeed in this not fail bc u cant take the wd. Please consider what everyone is saying! !! We r all here for u thru this process! Good luck
COMMUNITY LEADER
We have another girl on here that came off 8 mg and didnt experience any wd's either. Maybe you will be lucky too...
Yea strips made the taper a lot easier to because u can be pretty sure how much you are taking not just breaking it in little pieces and guessing
And, as an after thought, that was one of the biggest advantages to switching over to the strip versus the SL tab, much better absorption.
abritt...I understand totally what you're saying...just didn't want there to be any confusion with the term "ceiling dose" being used, that's all.
It's all good.
It's all good.
You misunderstand what I'm saying here the ceiling effect is at 4mg bupenorphine does nothing after 4mg now with that said taking 4mg of suboxone doesn't mean that if u take more nothing happens because when u take a 4mg strip/pill whichever itis you are not getting the full 4mg into your body because the BA is not 100% but I still stand by taking 32mg daily is way to much but my opinion is my opinion and I respect everyone else's as well
ABritt
ABritt
Yea that is how my doctor was I went actually all e way to .25 every other day for 4 well I guess actually 8 days but four doses and jumped off and withdrawal were little to none
And actually, the typically stated dose for the ceiling effect IS actually 32mg.
Most people, once stabilized off their DOC can be maintained at quite a low dose of Bupe. The common misconception is, the heavier the opiate user, the higher the dose that is needed.
That may be true for the induction dose, and for about the first 2 weeks, but then most everyone can easily be maintained at a low dose, 1-2mg daily. Obviously, that varies from person to person, and certainly there are situations where a person may need a higher dose.
Most people, once stabilized off their DOC can be maintained at quite a low dose of Bupe. The common misconception is, the heavier the opiate user, the higher the dose that is needed.
That may be true for the induction dose, and for about the first 2 weeks, but then most everyone can easily be maintained at a low dose, 1-2mg daily. Obviously, that varies from person to person, and certainly there are situations where a person may need a higher dose.
To give you a basic idea, at 32mg of Buprenorphine equals about 800-900mg Hydrocodone (Vicodin). I'm sorry, I don't care how resiliant you are, this is just setting yourself up to fail. You would be MUCH better off if you can taper your dose down MUCH MUCH lower. The Sub doc I worked for required a person not jump until they got down to at LEAST 0.5 mg/day.
This is one of the MANY suboxone/subutex stories I see where the prescribing doctor apparently did not know enough about the suboxone because there is absolutely NO REASON for anyone to take 32mg of subs a day because at 4mg the ceiling is reached and studies show that at the ceiling I believe it's covering 97-98% of the opiate receptors which with help or eliminate withdrawal and curb cravings. Unfortunately there are a lot of doctors that took their 6-8 hr class to be able to prescribe it so they can make a killing giving it to whoever is willing to pay them 1200-1500 dollars up front to be put on suboxone therapy I'm not saying by any means all doctors are only doing it for money but unfortunately there are ALOT of them that are. I am no doctor by any means but I have learned about many many drugs the hard way unfortunately
If u can I would STRONGLY suggest tapering off suboxone or subutex whichever because the withdrawal from it is pretty close to the same from oxycodone only a good bit longer and if tapered down to very low dose like all the way to 25mg you can make the withdrawal from the subs little to none(physical withdrawal). And to weaver not tryi g to make u look dumb or anything like that but the ceiling effect of bupenorphine I think that's how u spell it which is what suboxone is is at 4mg not 32mg
Good luck and Godspeed
ABritt
Good luck and Godspeed
ABritt
How long where you on the subutex? At such a high dose, it wouldn't surprise me if it takes 7 days to really feel the withdrawal. You have a lot of reserve sub in your system. Subs have a ceiling effect at 32 mg, and you had a lot more than that in your system. Atthebeach explains this well. Keep posting for support, but you may need to consider a taper, time will tell. Good luck.
no theres no reason its just that ive been through this before back when i was abusing oxycontin and oxycodone before i started subutex. i know what to expect. i just dont want to taper because i want to get this over with asap. im very resilent to things like this as well
no i havent been takin anything else. today is the fifth day and im experiencing very mild w/d symptoms but nothing to complain about yet
Great info from Debbie. Yes, due to the long half life, it isn't at all unusual to not feel w/d symptoms with Sub for a few days. Are you taking ANYTHING else? If not....you should be feeling it anytime now, and I hate to say, at the daily dose you were taking, it's likely going to be VERY rough.
I would STRONGLY recommend you doing this properly...and taper slowly, under the care of a good sub doc. A good clinic can transition you into a program, a lot of people who were taking subs on the street decide to do that...and start working a real program.
PLEASE look into it. Unless you're taking another med that is blocking, or helping mask the w/d, you are in for some pretty ugly days. People jumping off at 2 mg have a hard time, so imagine what it would be like for you?
Best of luck, please update your thread when you can!
I would STRONGLY recommend you doing this properly...and taper slowly, under the care of a good sub doc. A good clinic can transition you into a program, a lot of people who were taking subs on the street decide to do that...and start working a real program.
PLEASE look into it. Unless you're taking another med that is blocking, or helping mask the w/d, you are in for some pretty ugly days. People jumping off at 2 mg have a hard time, so imagine what it would be like for you?
Best of luck, please update your thread when you can!
If you don't mind me asking is there a reason you could not taper down and had to go cold turkey? And I completely agree with the other post when I was back and forth from suboxone and my doc it would usually be around 24-36 hours before I would start withdrawal from suboxone wearing off.
Question- Once I stop how long will it take before I feel any symptoms?
Answer- The half life of sub is about 37.5 hours, this means that it will take your body about a day and a half to expel 50% of whatever you took 37.5 hours prior. { If you took a 8mg dose at 8am you will still have about 4mg of sub in your body at 9:30pm the next day} You also have to take into consideration all the doses you took prior, they also stack up. So a 8mg dose you took almost 5 days ago will still be equal to around 1mg still in your body, plus add the amounts of all the doses after that together. This is why a low long taper is so important once you decide to quit. Especially if you are physically addicted to the sub. A lot of this half-life stuff has to do with how fast your metabolism works, but you will normally start feeling actual wd symptoms 24 to 72 hours after your last dose..The onset of the ACTUAL wds are watering eyes, yawning constantly, feeling tired and sluggish, about 12 hrs later the more harsher symptoms begin to appear.
How long the sub wd's will last, depends on two very crucial factors.
1) How long have you been on the sub for?
2) Did you taper? What stabilized dose did you jump off at?
Answer- The half life of sub is about 37.5 hours, this means that it will take your body about a day and a half to expel 50% of whatever you took 37.5 hours prior. { If you took a 8mg dose at 8am you will still have about 4mg of sub in your body at 9:30pm the next day} You also have to take into consideration all the doses you took prior, they also stack up. So a 8mg dose you took almost 5 days ago will still be equal to around 1mg still in your body, plus add the amounts of all the doses after that together. This is why a low long taper is so important once you decide to quit. Especially if you are physically addicted to the sub. A lot of this half-life stuff has to do with how fast your metabolism works, but you will normally start feeling actual wd symptoms 24 to 72 hours after your last dose..The onset of the ACTUAL wds are watering eyes, yawning constantly, feeling tired and sluggish, about 12 hrs later the more harsher symptoms begin to appear.
How long the sub wd's will last, depends on two very crucial factors.
1) How long have you been on the sub for?
2) Did you taper? What stabilized dose did you jump off at?
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