Dangers of mixing

Can prescription meds block the effects of cocaine, making the user more susceptible to overdose due to the lack of feeling? Supposedly there is no medical treatment for cocaine, like there is for opiates.

Antidepressants, other stimulants, subutex?

[J T Junig, MD PhD]

Some meds can have very dangerous interactions with cocaine-- MAOI's in particular would be a horrible mix, and would likely cause a stroke or fatal arrhythmia.  The modern antidepressants are not as bad in combination with cocaine as are the older medications like nortriptyline.  The problems are not so much the lack of feeling as they are related to potentiation of cocaine by meds that affect serotonin and norepinephrine-- namely the antidepressants.

There is no 'Suboxone' for cocaine, but there have been studies supporting one drug or another for reducing cravings for cocaine.  I have not been that impressed with anything that has been put forward so far.

[mariposa99]

A related discussion, Cocaine, antidepresants, sores, insomnia oh my! was started.