Aa
A
A
Close
363243 tn?1331037450
ACTH Reactions
Has anyone had a bad reaction to the ACTH stimulation test? I need to have it done and I have trypanophobia (fear of injections) amongst a slew of other phobias. I think my endocrinologist uses 250mcg of cosyntropin.
Cancel
6 Answers
Page 1 of 1
657231 tn?1453836403
I only got cold and they gave me a blanket.

Some flush - the worst I have heard and only in one or two people at most was nausea.

There should be only one IV and all the testing can be done via the one. Try to remain calm so the test gets the stim from the test, not the anxiety....
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
363243 tn?1331037450
I had the test and I didn't experience any symptoms. I was very anxious when the cosyntropin was injected but I think I calmed down 30 minutes later...I hope I did anyway:(.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
657231 tn?1453836403
Let us know the results. Glad you had a nice, calm test despite misgivings.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
I had the test last year and collapsed soon after the injection. I don't feel I've had a satisfactory explanation, but apparently it is extremely rare to have this response.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
363243 tn?1331037450
Sorry that you experienced that.  I'm not sure what would've caused the fainting.  Had you been diagnosed with AI or Addison's prior to the test?

I forgot to mention my results:
Time    ACTH  Cortisol
0 min  16.4       4.4
30 mins          20.8
60 mins          24.1

My endocrinologist did not give me a diagnosis of Addison's because I reacted to the cosyntropin, but I was told by someone in a group that I belong to, that I failed the test before I started it.  My baseline cortisol was very low and after the injection I produced what a normal healthy person produces before the injection.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
657231 tn?1453836403
You were below range - but your adrenals did react to the *stress* of the agent so technically, you are ok.

If though you have low sodium readings and consistent low cortisol readings, I hope the doc keeps an eye on you - as this may change in the future... that can happen (or like me, I was always low in the morning and high at night - I had the opposite disease!).
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Your Answer
Avatar universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
Submit Answer
A
A
Recent Activity
1817063 tn?1317204337
Blank
teo1958 is ... Comment
Jul 28
Avatar universal
Blank
5665 commented on Think LYRICA was culp...
Jul 21
363281 tn?1353103243
Blank
SassyLassie commented on I had no idea there w...
Jul 18
Top Thyroid Answerers
Avatar m tn
Blank
gimel
MI
657231 tn?1453836403
Blank
rumpled
Northern, NJ
Adrenal Insufficiency Community Resources
Top Thyroid Answerers
Avatar m tn
Blank
gimel
MI
657231 tn?1453836403
Blank
rumpled
Northern, NJ