Cortisol spike at night

I am a 35yo male and have been suffering form severe depression and low libido so I had some testing done.  I submitted a saliva neuro adrenal test by Genova labs and all my neurotransmitters were way low and the cortisol levels are as follows...9:30am=5.2 ( range 7.0-10), 2:30pm=8.3 (range 3.0-6.0), 7:30pm=13.8 (range 2.0-4.0), 12:30am=8.1 (range <1.5).  So my cortisol is spiking at 7:30pm which is completely backwards.  My DHEA was 285.2 (range 63-644).  My libido and energy are severely low and have been expreriencing severe depression for 4yo.  I was on narcotic pain medicine through a pain management doctor for a sever knee injury for 5 years and when I detoxed from the pain meds I have had all the symptoms stated. I as well I just had my testosterone checked and haven't received the results yet.  Any help is much appreciated!  Thanks in advance...

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High cortisol at night is indicative of Cushing's syndrome.

It also lowers testosterone. Your symptoms are consistent with Cushing's. There is no one test to rule it in or out - so you need several sets of different tests as well as imaging to find out if you have it as well as to determine source.

You need a decent endo that has tested for it and really treated Cushing's (lots say they have but really have no idea).

The health pages has some links to help. I had it myself.