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What is Normal Ranges for Cortisol, Serum Test
My result came back very normal, but I don't even know what is normal. Does anyone know the ranges for normal for a blood test for Cortisol, Serum (ug/dL).  Mine was 16.3 at 1pm in the afternoon.
I'm having severe symptoms that are affecting my day to day functioning and growing more constant now and I need to be my own doctor and try to figure out what could be wrong with me.  A year ago I was diagnosed with a Benign
(Adrenal adenoma) spot in my Adrenal.  Can you help?  Just really curious as to what the test results mean.
Is 16.3 very normal for afternoon?  Does anyone know??
Thank you kindly,
Susan
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1134679 tn?1260570198
Normal values are as follows:  (per Quest)

ACTH, plasma                      5-27 pg/mL
Cortisol, AM                         4.0-22.0 mcg/dL
Cortisol, urine                       4.0-50.00 mcg/24 h
Insulin, Fasting                     0.0-17.0 uIU/mL

No endocrinologist will base a diagnosis on a random cortisol since your cortisol levels change periodically during the day.

The true levels are to be taken before 9 am.

ACTH is produced in the pituitary and stand for "adrenocorticotropic hormone" and directly effects probably every cell in your body, have a direct impact on your blood vessels and blood pressure.

Adrenal glands produce cortisol.

Pancrease produces insulin.

If your AM cortisols are way below normal it's called Addison's Disease; too high is called Cushings Syndrome.  They are treated very differently.

Let me give you a kind of down and dirty idea of what happens... believe me it's more complicated than this, but we'll try....

Let's say you eat some sugar, your pancreas produces insulin to break it down, but the insulin doesn't know what it's suppose to do, so the pituitary kinda talks to the adrenal and says to send out some cortisol so that the insulin can get it's signal on what to do.

Consequently, a lot depends on if you're on the high side or low side...  it's not something you can ever ask anyone on here about unless you can say... I have Addison's or I have Cushings, pheochromocytoma, pituitary tumor or whatever.....

I hope this helps you out some....
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You really have to self,Keep up with what is happening to your cortisol, my doctor forgets all the time to have me tested!- I constantly have to remind him eq yr. I went to Mayo clinic and had a booster shot (they called it) to stimulate my pituatary gland to start producing cortisol. Yet, eq yr. doc forgets. I have to have pain shots of steroids and can not do this if my cortisol level is tooo low. The doc office always says I have a great blood test. I get the shots and I find out my cortisol is 1 or less. Evidentally they think is great, is not so great to me.
Good luck to you.
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Just curious?
I took a Cortisol Blood Test @ 1pm in the afternoon and it was
16.3 mcg/dL.  What do you think or is that anything to even think on?

Thank you!
Sincerely,
Susan
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726204 tn?1285879778
I to have a growth on my adrenal glands and am having severe daily symptoms.

Urine tests for pheochromocytoma are negative.  I have had 2 morning cortisols taken and are both at the bottom end of normal then another one done that was high.  I had a dexamethasone suppression test that was normal.  My endo ruled out addisons on these morning cortisol levels!!!!  They originally thought I had addisons though.  I have just had laying and standing Renin and Aldosterone levels done but am awaiting the results.

I have now developed bad orthostatic Intolerence and have a 'probable' dx of POTS - I am awaiting to be assessed by the UK's leader in dysautonomia.  

What are your symptoms?
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I was at the ENDO FOR THE 1ST TIME...BLOOD CORTISOL LEVEL CAME BACK 4.0 AM DRAW. HE NEVER CHECKED IT AGAIN...AND SOMEHOW CHANGED BLOOD DRAW TIME TO AFTERNOON....TOLD ME I PREMATURE OVARIAN FAILURE, HASHIMOTO'S (THYROIDITIS) STARTED ME ON SYNTHROID .O5
SECOND TIME WENT TO HIM HE RETESTED ME BUT NOT FOR CORTISOL SERUM LEVELS!  WAS ABOUT TO FLY TO CLEAVLAND CLINIC FEELING ON THE VERGE OF DEATH....FINALLY AFTER 3 YEARS FOUND A LOCAL DOCTOR(PLANE WAS DELAYED TO CLEAVLAND DUE TO WEATHER) AND HE MENTIONED MY SCAREY CORTISOL LEVELS AND ADDISONS DISEASE...HE RETESTED MY AM CORTISOL LEVEL AND IT WENT DOWN TO 3.86 SERUM LEVEL ALSO SAID SYNTHROID WOULD AND COULD MAKE THE CORTISOL LEVEL DROP FURTHER!  I BELIEVE THIS DOCTOR HAS SAVED MY LIFE...AS AN ADDISONIAN CRISIS WAS CLOSING IN! WHY ARE SO MANY DOC'S ILL INFORMED!  i HAVE BEEN DEALING WITH HEALTH ISSUES MY WHOLE LIFE LIKE OPEN HEART SURGERY AT AGE 7....TONS OF AUTOIMMUNE DISEASES AND NOW THIS.  SOMEONE SHOULD HAVE CAUGHT THIS SOONER!  
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I just came across your post about your cortisol levels and being hypothyroid. I have issues with both too and am trying to find a doctor to help me. So far not much luck.

How are you feeling these days?

Deserie
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657231 tn?1453836403
Just FYI - the person you are writing to is from a post in 2009. I am not sure they are checking over here or are still around. Some are or are not.
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In 2009 I too had an adrenal adenoma, am cortisol was 3.2, 24 hr urine was normal.  I have hypotension, fatigue, muscle weakness, and my new am cortisol is 11.1 which is normal.  I had that adrenal and adenoma removed, so I want to make sure that the remaining adrenal is functioning the way it should.  I feel like I'm talking to a brick wall, and not getting anywhere!  Please help
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657231 tn?1453836403
Your doctor should order a stim test. A regular test is not sufficient.
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hi ,
i was tested serum cortisol  and it was  21     morning   range   5-20  (h 11 am)
and prolactin                                               14      woman    range   4,6 - 25

when i was in my twenties sometime i came back form work vomiting and with strong nausea, doc would shot me some adrenal extract and i used to have immediate relieve...I mean... stress is my life companion ...the situation is messy because i also have no thiroid but i just want to ask you if always waking up early in the morning and not being able to fall asleep again despite been very tired and the above cortisol value could be a sign of adrenal weakness...


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657231 tn?1453836403
I would say it is not a sign of adrenal weakness but rather Cushing's syndrome.

I would look that up.  
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