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My sister had a reaction to bananas years ago where after eating them her tongue became very swollen and she had difficulty breathing. She went to the hospital and they gave her a shot benadryl. She was told she had an allergic reaction to bananas. She stopped eating bananas since and hasnt had another episode. Try to keep track of what you eat and see what food(s) is causing the reaction.
It happens with my throat. When it does, I do not take a Benadryl pill, but instead take sips of liquid Benadryl (used usually for children). This gets the anti-histamine where it is most needed in jig time.