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I also experienced a horrible breakout of hives! The only thing that I did differently to cause the hives was take fucothin. I am barely starting to get rid of them and its been two weeks. I broke out all over my entire body, even my handsHand or foot spasms Hand tremor and feet were covered with hives. I even went to see the doctor 3 times and they had to prescribe me several medications. It was the most horrible experience ever. I didn't take them long enough to lose weight because the hives started forming and I stopped the pills. I was disappointed that I couldn't take them.