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I call them internal hives!

The beginning of the story is that about 7 years ago I started getting chronic sinus infections.  From that I would go to my doctor about monthly with sinus infections.  He would give me a perscription and a medril dose pack (prednisone) to take care of my infection.  After a few years of this, I started to break out in hives so no more of that medicine. And so I would take something else next time.  We decided that I am now allergic to omnicef and sulfur.  The worst part about the last hives case was when the hives went away with benedryl I was in so much "joint pain".  I mean for 2 weeks I was in the worst pain I have ever felt- my doctor and another allergist were taking blood tests, giving me perscription ibprophen, and x-raying my hands.  I say that I was like a 100 year old lady with arthritas.  I couldn't move.  On my second trip to the ER I demanded to see the head of ER.  He listened to my story and simply said you need more prednisone.  When you take prednisone with an antiobiotic you get worse if you finish the prednisone before your infection is gone!  Someone who understood what I was going thru.  From that I got a shot of Decaral? and was on 60mg of prednisone for a week and then started to cut back till I was off the prednisone.  So that whole thing was about 4 years ago.  Now I was diagnosed with Graves disease and had been on meds for about 2 weeks when I got hives.  The hives lasted 4 days so I would say its the meds that caused it since they lasted that long.  The "external hives" are gone since I was taking benedryl but now my hands hurt.  That same pain I had 4 years ago and my doctors now think I'm nuts.  I am about ready to go to see the ER doctor again.  I want to know what this is and why it is happening?  I have not taken prednisone since that time 4 years ago but is that what I need now?  
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Avatar universal
Hi Rachel,

I see that this post is pretty old, and hopefully you have resolved this issue since.  But I did have questions:

1.  Despite the external hives, did the prednisone help your joint pain?
2.  Does the Benadryl take care of the hives, if not the pain?
3.  What medication were you given for Graves' disease, and why was that the diagnosis?

It sounds like something autoimmune is in play.  Maybe rheumatoid arthritis?  Lupus?

Whatever you do, get enough sleep and try not to stress, because too little sleep and too much stress make everything worse, especially autoimmune.
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179332 tn?1273247359
I couldn't be MORE serious to say that you have been on WAYYYY to many antibiotics and probably have a Candida Overgrowth causing ALL your symptoms because I would swear what you have written here - is what I HAVE BEEN GOING THRU TOO!!!!!!!!!!!  To top it off - Steroids make the candida grow more!!  To test for Candida - ask your doctor or allergist for a stool sample test and a blood test - I send my test into Genova Labs (i think it's Smoky Mtn Labs now)...it's $46.
with the results being positive on me for candida - I take nystation powder now and stay away from sugars and things that produce my reactions!
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