I have a problem with my shoulder where it dislocates all the time so i end up in the E.R. allot.
About 4 months ago i was given morphine before they put my shoulder back in and i developed a raised itchy rash where they had injected it on my arm. The next time i had morphine was about a month later (shoulder again) and i got a rash all over my body so they gave me an shot of antihistamine (poor spelling) and the rash went down.
So 6 weeks ago i had surgery on my shoulder and told the doctors about the reaction to the morphine they said they'd put a red band on me to make sure i wasn't given any morphine but they didn't in the end. When i woke up from the surgery i was ok but i couldn't stop my legs shaking and then my whole body started shaking and i couldn't stop it, i was pretty out of it but the nurses and doctors seemed pretty concerned and gave me a shot of something that made it stop.
Does this mean i have an allergy to morphine or does this happen to everyone?
Hi, welcome to the forum, your history is suggestive of that you are having drug allergy to morphine. Some patients have reported to have itching (in more than 10%), rash and development of hives.
The possibilities for allergy are due to presence of Phenanthrene in opioids. You can even develop hypersensitivity reactions to other phenanthrene derivative opioid agonists (codeine, hydrocodone, hydromorphone, levorphanol, oxycodone, oxymorphone).
Another precipitating factor is morphine is known to release histamine which can further precipitate the allergy. Subsequent exposure can be life threatening. Hence, future exposure to such drugs should be avoided. Take care and regards.
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