I had five pure titanium dental implants five weeks ago and at the same time preventitive penicillin taken orally and in tablet form. The following day an area around my groin broke out in a typical hive rash. this soon spread to my torso, arms and shoulders. WEnt back to the dental surgeon and he prescribed a none penicillin antibiotic the course of which I completed,taking 7 days. The rash did not recede so went back to him and he gave me two injections of hydro-cortisone (100mgx2) which seemed to help. Since then the rash has developed into an eczema type rash. My GP prescribed a cream which does not seem to help and the rash seems to come and go with varying degrees of intensity and a peculiar prickly itch which is bordering on the painful. Cortizone cream helps a little but I am concerned that the implants might have something to do with this violent reaction to the surgery/antibiotic/ trauma of the surgery. My dental surgeon is a respected and senior member of the profession and has had no cases of this sort in over three thousand ops. Any ideas? Philip
Despite of the fact that titanium is usually considered "intert", one can develop allergy to it. Physico-chemically it belongs to so called transitionmetals and those metals can bind to enzymes and other proteins in the body and thus trigger inflammation.
You can read more how to test against titanium with help of blood test -MELISA at the following website:
Thank you Melisa. I saw my Dr again yesterday and he was certain this damn rash was a typical reaction to the medication Amoxicillin. My dental surgeon, who is a specialist in implant surgery, has never seen it before, after over 3000 separate operations and claims he has researched the "problem" and there is no published papers describing titanium side affects. So I will continue with the antihistamine and anti itch creams until next week and see the doc again if no improvement is evident. Any one out there has had any experience with penicillin allergies?. Are there any cardinal symptoms of titanium allergy and notes on it's progress? Do they come in groups or single symptoms? My problem is the symptoms started at the same time as I had the implants and ingested the Amoxicillin so don't know which is the culprit. Would I react so quickly to titanium seeing that it is an "inert" metal. as ever Philip
I am sure you have a brilliant dental surgeon but I can assure you, allergic symptoms after titanium implants exist and might be more common than expected. The best way is to recommend your surgeon to look at our website: www.melisa.org and read cases where health problems disappeared after removal of implants. There are also several scientific articles on this very important issue.
It seems that allergy to titanium as well as other side-effects (for example cardiac problems, fatigue) are increasing. This might be due to the widespread use of titanium dioxide as a colouring agent E171 in foodstuffs, medicines, sunscreens and other items.
Regarding the ampicillin rash, even this seemingly different event might be connected with metal exposure: the major metabolite of penicillin in vivo is penicillamin - a drug known for its metal-mobilising properties. In people sensitized to metals, mobilisation of the allergen might results in a skin rash. These effects are well-known to doctors using D-penicillamin for treatment of various diseases such as multiple sclerosis.
If you, by any chance, suffer from allergy to nickel or other metals or if you have silver or gold fillings in your mouth, this might increase the probability of metal sensitization.
The MELISA blood test can objectively diagnose allergy to the metals you are currently exposed to.
I hope this helps.
Associated Prof of Immunology
University of Stockholm, Sweden
Dear Professor Stejskal, Many thanks for taking the trouble in answering my cry for help. The implants used in my operation were manufactured in Sweden and my dental surgeon assured me they were the best! I will pass on your helpful advice to him and my GP very quickly and hope they will take up your invitation to log on to the web and look at the information on www.melisa.org. Your comments and opinion are much appreciated. Tak. Philip
I am contemplating having some titanium implants, but remember what how ill I became with terrible rashes, joint pain and low grade fever from nickel crowns (The dentist promised noble metal and lied for extra profit.) I am wondering if your implants contain aluminum or another metal? See link: http://www.*************.com/Composition_Of_Dental_Implants.php I can't even use deodorant with aluminum because it causes weeping sores and swollen glands.
"The grade five titanium named, Titanium6AL-4V (signifying the Titanium alloy containing 6% Aluminum and 4% Vanadium alloy) is believed to offer similar osseointegration levels as commercially pure titanium. Ti-6Al-4V alloy offers better tensile strength and fracture resistance. Today most implants are still made out of commercially pure titanium (grades 1 to 4), but some implant systems (Endopore and NanoTite) are fabricated out of the Ti-6Al-4V alloy. Implant surfaces may be modified either by plasma spraying, anodizing, etching or sandblasting to increase the surface area and the integration potential of the implant."
I received 3 dental implants in December 2010. A few weeks after that I started to have inflamation on my thighs with painful eruptions (or bumps). Since that time, I have developed much inflamation on my thighs, calves and arms. I have red itchy, painful bumps all over me. I can only wear very loose clothing because it is hurts for me to have clothing rubbing against my skin. I have been to about many dermatologists and they don't know how to help me. I have been given antistimines, cortisone creams and predinisone. The cortisone cream helps, but I don't want to use it anymore because I am afraid of causing more damage to my body. LondonStreet, you are not alone. The doctor that put in the implants said that it is impossible to have a reaction to titanium. The dermatologists agree. They don't believe that implants in my mouth could be causing me to have skin problems on the rest of my body.
My mouth looks perfect. the gums are very healthy and there is no pain.
I'm afraid I am going to have my perfect implants pulled out. The cost of all of this has been so expensive, not to mention how very upsetting it is. I simply don't know what the answer is.
thank you so much for the information! Two days after implant surgery I noticed an itchy rash on my neck, which spread to my lower back. It drives me crazy, but after reading your post I do not feel so alone!
I happened to put in implants and rashes tonight..I have had 6 implants put in..2 were put in 2 yrs ago and I just had 3 more put in about 3 months ago. About 6 months ago I start with 3 little spots below my right elbow..All of a sudden about 1 month later I had a rash all over..My arms, breats, both legs, thighs..abdomen and back..It itch is so bad I can hardly stand it anymore..I have been to 4 different dermatologist even went to allergist/immuologist..No one can figure this rash out. My levels of IGG, IEG, IAG are all off..One is extremely High and the other extremely low..They know I have some type of immune problem, however, they don't know what it is..I am going to the University Of Penn to their dermatologist to see if they can figure it out..Now I am wondering could it be from the implants!
I also have develop acne like rashes, and red bumps on my face soon after my dental implants were put in. I've been to dermatologist, allergist, gp and going to rhuemotologist soon.
The dermatologist says it is acne rosacea. It may be a coincidence but it seem to suddenly develop around the time I had my implants put in. So far, I've been on a lot of oral and topical meds for the acne rosacea but it doesn't seem to be helping. I am on the healthiest diet every so it can't be my diet. I had a metal allergy test done and it says I am not allergic to titanium but highly sensitive to mercury. My dentists claims there is no mercury in the implants/ or materials but I am really not sure at this point.
The bumps on my face is really bad and complexion is terribly maybe because of all the medications. I had clear skin prior to the implants. I don't know what to do- this is so frustrating. I don't want to go out or see anyone. I do not want to keep taking the oral/topical meds if it really is not helping me.
I had 8 implants put in so I think it is very hard and would be extremely expensive to remove but I don't know if that will help my condition.
I don't have any other rash on my body...just my face.
I put an implant and spent more than $5000 in sinus lift and implant. Only after 3 days, I started getting rashes all over my body. I have been through several dermatologists and allergists. They cannot find the source, except prescribing the heavy doses of steroids. Now finally, after 3 and 1/2 months I have taken the appointment to remove the implant, because I cannot find any other reason of rashes except allergy with titanium. I will let you know once implant is removed.
Since I put a dental implant, I started getting rashes on legs. I have been to deifferent specialists and they all have suggested different things--medicine reaction etc. After testing over 4 months on different things, nothing came back. Mouth was perfect, no inflmmation in the mouth or gum. Finally I decided to take the implant out, since I could not find any other source. Now things have improved. But probbaly it would take some more time to get to the normal.
Hello all. I have finally removed the implant today after about 4 months of continual rashes over my Hands and legs. I used tons of steroids and antihistamine. I used to be a healthy guy but became too weak within 4 months after using these stupid medications. Specialists were equally stupid as they would say there is no inflation in the mouth and gums so it could not be titanium allergy, since rashes were red and growing and healing with steroids, then coming back in the hands and legs. Finally, against the advice of all specialists, I have removed the implant. It was not too hard to remove it. It took about 20 minutes. I do not know the effects yet, since I removed it only couple of hours ago, red rashes are still visible. I will know only after some days whether my decision was right or wrong.
I have also developed major skin/acne issue on my face right after receiving my dental implants. I have tried all types of treatments...topicals, oral antibiotics, acupuncture, etc. and NOTHING has worked so I'm wondering if it is from the implants. I have 8 implants and the thought of removing all of them seem daunting..but don't know what else to do
We should all be concerned that we go to our doctors and share the experiences, stories, scientific articles we have read on the Web and they swear up and down that they have never, ever heard of these things! Do they not keep up on the latest technologies, research, and updates in their field?? I would think that they are required to go back for training every several years in order to have their licenses renewed.
I told my implant doctor about the possibility of allergies to the implants after I went into his office with my two eyes swollen up like boiled fish. He said he had "never heard" of anything like what I was experiencing and admonished me for "believing" things I read on the web. :-)
Actually, my reaction occurred 6 months after the two implants were put in and a couple of weeks after the abutments were screwed in. The metal abutments were exposed in my mouth. It must have been system overload!
At least my implant dentist is trying to work with me. I had the abutments removed today and he said to get back to him to see how I am feeling. My complaints was sinus pain, pulsating gums, heaviness in eyes, and a crook in my neck and back from not being able to position myself at night for a restful sleep. Deep down inside I know it is the implants. I NEED TO GET ON WITH MY LIFE!
Today I go for a facial CT scan of the sinus to make sure the implant is not in the sinus cavity. I've asked an oral surgeon to do this just in case I have to have the implants removed. My implant doctor will do it with just local anesthesia and this scares the heck out of me. Of course, oral dentist tells me he will not remove them if he doesn't see a problem with them ... no matter what I say. It's not his work so I am not going to press him.
On Thursday, I am going for the Melissa test. I'm concerned about spending this amount of money because some people say it comes back "negative" and they still have problems. I'm wondering whether it is going to be worth it.
Other doctors I have had to see on my journey - allergist, ENT, endodontist, general practitioner.
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