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testing for autoimmune urticaria

testing for autoimmune urticaria

i have had hives for over 10 years but no body new why until i found theinternational chronic urticaria society that listed the signs and symptoms for autoimmune urticaria and it was a feeling of  finally thinking that i wasnt crazy. now im trying to figure out how to comfirm this diagnosis with my doctor. i know that there isnt many tests to difinitivley diagnos this disorder. the only one i know of is a IgE antibody test and a somewhat contriversal serum skintest is there any other test that can be preformed to diagnos this disorder. please help  
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“The 'gold standard' laboratory test for AICU is the demonstration and measurement of histamine (or other mediator) release from target basophils or dermal mast cells. Basophils are normally obtained from healthy donors. Basophils from both low-IgE and high-IgE donors should be used to enable identification of patients with anti-FcεR1 or anti-IgE autoantibodies. Dermal mast cells are obtained from skin removed during circumcision.[3,4] Alternatively, a rat basophil leukaemia cell line transfected with the genes that code for the α, γ1 and γ2 chains of FcεR1 can be used.[6] These cells express functioning high-affinity IgE receptors, and can be used to detect anti-FcεR1 autoantibodies by using release of β-glucuronidase histamine or serotonin as quantitative markers of activation.” Refer: http://www.medscape.com/viewarticle/461843_3

Another test is punch biopsy of the urticarial lesion. Refer: http://www.wrongdiagnosis.com/a/autoimmune_urticaria/diagnosis.htm

Hope this helps. It is difficult to comment beyond this at this stage. Please let me know if there is any thing else and do keep me posted. Take care!
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