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Yes Tanns you're right. It is possible. I had allergic reactions to penicillin after years of using it without incident. Now for this child, if you did not give him any medicine, then it could be food allergies, unless it is actually chicken pox. Any high fever? Any other symptoms? I think the Benadryl is a good start, but don't expect it to remove the red spots instantly. It will take some time maybe 2, 3 or more days. But you should continue giving it to him and see the family doctor as soon as possible. Good luck..
Just a thought.......