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Info needed regarding cancerous lymph node removed
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Info needed regarding cancerous lymph node removed

Hello, I'm interested in finding information regarding the safe use of using a multiple mushroom supplement for humans called Host Defense.  My kitty, Foo, had a cancerous left cervical lymph node removed on Oct. 13.  The pathology report, done at the University of Penn., came back with much uncertainty as to what it actually was.  It was diagnosed as an anaplastic round cell tumor, with possibility of it being an unusual B-cell lymphoma, anaplastic lymphosarcoma, and even in some areas, a metastatic amelanotic melignant melanoma.  From what I understand if this was not the only site, this is a fatal cancer with little or no treatment options.  Is it safe to give the Host Defense supplemt which is supposed to raise immunity in some cases 300%?  I also saw something that in elevating immunity, the B-cells are involved.  If the cancer was a B-cell lymphoma, would the supplement cause the activation  or speeding up of this type of cancer?  Please, I am looking fro treatment options.  As of now,  he appears to be acting completely normally.  
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I am sorry about your cat!  

I looked up Host Defence.  It contains important cancer fighting and immune stimulant mushrooms such as:Maitake, Royal Sun Agaricus, Chaga, Reishi Mycelium, and, most importantly, Cordyceps.  I have found that a variety of neutraceuticals are usually necessary to combat cancer though, not just one product.  

In addition to Host Defence the following may be helpful additions to your cat's anti-cancer regimen:
Onco Support
Transfer factors
IP-6
Very high levels of fish oils (30 mg/kg/day of DHA)
Acidophilus at 2-8 Billion CFU/day
Laetrile (100 mg BID (AKA: Vitamin B17) www.laetrilesupply.com)
Neoplasene
Pepcid, Sucralfate, and Reglan (to help your cat tolerate the Neoplasene)
High doses of Turmeric or Curcumin (cumin)

Onco Support, Neoplasene, Sucralfate and Reglan are available from your veterinarian or a holistic vet if your vet doesn't carry them.  The other neutraceuticals are available at some health food stores or online.
11 Comments
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Thank you so much for the information and your sentiments!  Foo is a special little kitty adn I want to do what I can for him.  
I will look into these options and dicuss them with my vet.  
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Dr. Cheng,
I researched a little more about Neoplasene and have a few questions.  This supposedly attacks only cancer cells, but after reading about the injectable and topical effects, I am cautous to use it orally(internally).  If I may ask, what kind fo results have you seen using this (and the regimen you prescribed) in lymphomas/leukemias/blood cancers.  And if my vet doesn't have experience in this, could you suggest someone in northeast PA (I'm mear Wilkes Barre)?  I would love to meet with you, however Foo doesn't travel well.  
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You can talk directly to the creator of Neoplasene with questions.  There is a 96 page clinical guide that gives you all the info you could probably want.
http://buckmountainbotanicals.net/pdf/clinical_guide.pdf
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234713_tn?1283530259
I have had less side effects with neoplasene when given orally than topically or by injection.  We use it often and it has prolonged the life of many pets, but only in pets that actually take it.  It is vile tasting stuff.  The PolyMVA is not quite so bad tasting.  Wilkes Barre is about 2 hours or so from my practice.

Good Luck with Foo!
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Thank you Dr. Cheng, and thank you trainr.  
Dr. Cheng, I may contact you at some point.  
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I am asking for help from anyone who has used Neoplasene Oral suspension.  I can not get my kitty to take this and am looking for suggestions.  He's finicky to begin with and usually only likes dry food (Verus, Wellness - high quality human grade foods).  I talked with Dr. Fox, the creator of Neoplasene and his suggestion was to put it in an oil (salmon, tuna, sardine) and mix with a "meaty" food, keep offering this, and to not give in till he eats.  It is now day four and he wants to have his dry food - which I pureed and added water or oil - and he still won't eat.  He wants the crunchies.  I have also used canned Wellness, Organic SoBright, Halo, and even baby food.  Can someone help and maybe add other suggestions?  
Thanks to anyone who can help...
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Avatar_n_tn
Hey, Sharon,

I received your note.  I don't have an answer, but I can maybe help you think about it differently, if that might help.

If I understand correctly, the cat hasn't eaten anything for 4 days, which should mean it's ravenous and sluggish from lack of nutrition.  Cats are carnivorous and designed to eat meat.  Even if the cat is used to solid, crunchy food the natural instincts should be taking over when presented with meat when hungry.  Not eating meat when hungry is highly unusual for a cat.  I think it's more likely to eat disgusting-tasting meat (meat infused with Neoplasene)  than disgusting-tasting crunchy carbohydrate mix.  You can also try mixing with a small amount of water and squirting it down the cat's throat with a hypodermic (without the needle) syringe.  Have extra water on hand for the cat to wash it down and wash away the taste.

At this stage, and the cat not eating meat, I would definitely start injections, assuming it still won't eat and you can't squirt it down the throat.  You've already determined Neoplasene isn't harmful to normal tissue, so you've got nothing to lose; whether oral or injection, it gets into the bloodstream where it does tremendous good.

I'd ask the vet to monitor the level of inflammation once treatment starts because once Neoplasene unmasks the hidden cancer cells, the immune system will attack the cancer, causing high levels of inflammation.  You may also see high levels of antigens to the cancer cells showing in the blood.  These are all good things.

Hang in there.
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Trainr - Thanks for your suggestions - you are a Godsend.

I was actually able to get the full dose in him.  I posted in the forum with the details and would appreciate your guiI premedicated him with Reglan and let him eat normally - feeding canned organic human grade food (Wellness, So Bright, Halo). I then mixed the Neoplasene with with salmon oil, drew it up in a 3 cc syringe, gave it to him immediately after he ate, and then washed it down with water.  So far, four times and with no ill effects.  My only other question is, as far as your knowledge, this shouldn't effect the absorbtion at all so technically, he should get the right dose - correct?  The only reason I ask is that when I spoke with Dr. Fox, he seemed to stress that being creative with feeding is not a good thing, and mixing it with all the food is the way to go.  But wouldn't that process happen in the stomach anyway?

And as far as the swelling, there is a small amount but nothing major yet.  Does it take a couple of days, weeks?  He's only had full doses for a day and a half, and we haven't increased to the 120 mg yet (he's on 60 mg as of now).  He seems very bright and playful, not feeling bad or sick.  

Guidance and advise is appreciated.  
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Hey, Sharon,

I am so happy for you that you now are getting kitty to take treatment.

Regarding oral with or without food, I think the reason Dr. Fox stresses the feeding program isn't so much due to percentage-that-makes-it -into-the-bloodstream, but rather due to the fact the animal is likely to reject it unless you find an on-going method that works -- which, so far, always involves mixing with their food.  Altering feeding patterns lessens the likelihood that the animal will continue accepting oral treatment.  The treatment should work, if I understand correctly, even on an empty stomach.  The good thing is getting it into the stomach and eventually to the tumor(s) or other neoplasm.  

The oral dose limit is the level at which the animal can no longer tolerate the gastric distress.  The antiemetic Reglan increases that limit.

Again, I'm not a vet so I'm not qualified to give advice.  These are opinions I hold that seem to be reasonable and are based on observation and Dr. Fox's 96 page Clinical Guide (which advises care when treating cats as they have a lower tolerance, apparently).  

While the cancer is dying, the cat's temperature may go up due to the additional inflammation, for a while.  This is not unusual.  It's also not unusual to have to stop the treatment due to gastric distress for awhile, and then restart with no ill effects later.  I think the important thing is that you are using what appears to be the most effective treatment available for solid tumors.

Continued good health to your cat.  

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Avatar_f_tn
Hello again, - I need some more info if anyone can help...

In regards to Neoplasene treatment and effects - my Foo kitty was titrated up to a 90mg dose on the 15th.  Within 24 hours, there has been large amounts of swellings - not only in the original site, but 5-6 different ones, and on the opposite side of his throat.  I know this is how the medication is supposed to work, but how do you know it is not the cancer and to seek other treatment (steroids,etc) for the swellings.  I know the steroids would render the current treatment with the Neoplasene useless, but he is not feeling well at all.  I knew this would be part of the treatment, but at what point do you seek other support treatment options and what are they?  I don't think it is a crisis situation as of yet, but I'm trying to get info to avoid that.  I don't want to end up in the emergency clinic on Christmas Eve.  My vet has had no experience with this and I can't get in touch with the creator of the med at this point, so I'm asking anyone who has had experience.  This is stressful and scary to me and I love Foo, but I don't want to make him suffer.  

Dr. Cheng, can you use Poly MVA (as you mentioned befoer) as an adjunct to Neoplasene, or would it interfer?  Does it work in the same way?  

Thank you all for any advice you can give.  I apologize, but this is the only way I have found so far to get this information.  
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234713_tn?1283530259
Aleda M Cheng, D.V.M., C.V.ABlank
American Animal Hospital
Randolph, NJ
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