Buspar/zoloft

Can I take Buspar and Zoloft together?

[M4Y0U]

Yes the best place is to call at the pharmacy regarding interactions. You can also check on this websites for more details if you feel like the pharmacist haven't told you enough details or if you want to check yourself before you call. Personally I have several doctors/pharmacists applications on my iPhones (Epocrates, Skyscape, PEPID) I usually check interactions with Epocrates. Here is the website you can use if you don't have a iPhone - https://online.epocrates.com/home - You can check for interactions on this website and it's a trusted resource used by many physicians. Another good and free website is http://www.healthline.com/druginteractions - not as reliable and not used by physicians like Epocrates but better than nothing.

It's always good to call the pharmacist anyway but double checking is better and you know exactly what kind of interaction it is. Sometimes pharmacist will say there are no significant interactions when there can be a minor interaction like additive efffect interactions, increase/decrease, hepatic metab. inhibited, decr. conversion to active metabolite.

With Zoloft and BuSpar the interaction is a pharmacodynamic type interaction. There is an additive effect. Both increase serotonin levels. Contraindicated unless benefits outweigh risks and no alternatives available. It is all relative to the dose you are taking, careful dosage adjustments should be done if you intend to take both drugs.  

M4