Here is what I discovered recently. My depression and anxity come from brain damage from lack of affection and feeling safe as an infant and toddler. It has caused anxiety since puberty, which I have tried to "fix" for 38 years with talk therapy, 25 years in AA, the last 13 years on a series of antidepressants, which are now Wellbutrin 400mg daily and Buspar 40mg daily (both generic). The Buspar isn't quite working, so I hope my psychiatrist will figure out a better med for the anxiety when I see her next week (July 2009). Wellbutrin relieved the constant, stupefying fatigue I've had since I had mono in the late '70's, and that increased significantly when I started on SSRI's in 1995. Last year my new psychiatrist switched me to Wellbutrin, which has transformed my life. Apparently I had a big problem with dopamine that the SSRI's weren't addressing. I used to nap several times a week, including at work at lunchtime. Now I take a nap once every few weeks.
I have never had a truly intimate emotional relationship with anyone. I've had glimpses of it, but I think people detect my "intimacy anxiety" and it sounds an alarm. I've noticed the same thing in the feral cats and dogs I've rescued - too much affection and touching scares them, instead of making them feel good. And people who come to my pet adoptions, even those who have never had a pet, seem to sense that the timid dogs will never truly trust - and they don't adopt them. That's how I've been all my life. My outside seems OK - great sense of humor, smart, good at my job. Inside, I'm scattered, with a low hum of anxiety most of the time. I'm grateful to AA for reassuring me that "those of us who can't have families" can still be of service. And I do have several female friends that I socialize with - but who each have their own significant emotional problems to deal with.
The panic attacks and anxiety went away with Effexor, but I was also exhausted all the time. Two weeks after I switched completely from Effexor to Wellbutrin, after 12 years on SSRI's, I began to panic again, and couldn't leave the house for two weekends in a row. I remembered that I had some leftover Buspar from a previous attempt at fixing the fatigue, so I looked up the dosage, and took enough to relieve the panic, and function again. My psychiatrist agreed that the Buspar was a good idea, and I've been on it in addition to the Wellbutrin.
I found out about my brain damage just recently - Easter Sunday 2009, in fact, when I googled emotional damage, and found some articles on www.scholastic.com about what happens to children who aren't cared for as infants and toddlers. At first I was angry that I had spent almost four decades trying to figure out why I was crazy, and getting "fixed," when I was actually experiencing organic anxiety - my brain's inability to prevent the overactivation of my "fight or flight" feelings.
But now I'm off the hook. I'm not crazy, I have brain damage. I may not be able to recover from it completely, but I no longer feel like a deficient human. "It is what it is," as my friend Rebecca says. And I don't have to be afraid of myself anymore.