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I have been taking generic Zoloft 25 mg for about 7 weeks now. I do notice an improvement with my level of anxiety and my mood swings. Initially I had some increased anxiety, hot flashes and some GI problems. These went away after about 2 to 3 weeks. After talking with both my doctor and my psychologist, I have decided to increase the Zoloft again. My doctor suggested I do it slowly, going from 25 mg to 37.5 (1 and 1/2 25 mg tablets), and then increasing to 50 if I feel I need to after a while. My question is, could I see a return in the side effects when increasing the dosage? I know that the doctor is increasing it slowly to limit side effects, and says I should not have the side effects this time, but I would like some opinions from people who have been on Zoloft.