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RCA7591: Plasma level and tolerance

by Southie, Jun 03, 2009 03:08PM
ive been taking klonopin for almost 1 year.  never more than 1mg per day and always have taken 1mg either .5 bid or .25 qid.  if i wanted to stay on a total of 1mg a day, if i stopped taking .25 qid and instead took .5 bid, would this change in plasma levels increase the risk of tolerance developing.  i know you say tolerance isnt an issue bc constatn plasma levels are maintained.  so i dont want my plasma levels to flucuate if this is a problem.  if it isnt a problem, how often can i make a change?  or do i need to stay the same for a long time.  i DONT want to do anything that will cause tolerance.  i think im going to take .5 bid because i have a hard time taking a pill qid.  also i am now taking brand name klonopin instead of teva and can tell its more powerful.  .5 mg of klonopin is noticeably stronger than .5 of teva clonazapam.  so i am hoping that the .5 bid is just as good or better than the weaker teva at .25 qid.  i greatly appreciate your knowledge and willingness to help others.
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