I have been on 75 mg of Effexor 3x a day for 4 or 5 years I'm not sure. For the past three months I have had hives. My doctor tested me for a number of things and has come to the conclusion that she doesn't feel my anxiety medicine is doing it's job anymore. So she has decided to switch me to 20mg continual release form of Prozac a day instead. I asked her when she proscribed this should I switch straight across or taper the Effexor off. She said the switch straight across, that I would be fine. Well I have to say this is day two and I am sick to my stomach, jittery, and my emotions are all over the board. I'm starting to wonder if should of tapered the Effexor off. If anyone can give me some insight in to this I would be very grateful. Honestly I have not had that good a luck with doctors. My first refused to diagnose me with any disorder of the sort because he didn't believe in medicine for emotional issues. I was diagnosed by the ear specialist he sent me to for my blackouts, nausea and dizziness that I experienced every day of my life since I was 15. My new doctor doesn't seem that knowledgeable either. Any advice would be great thanks!