I have a sinus infection. I also have had anxiety and depression issues flare up earlier this summer. I was given a new antidepressant and anti psychotic, and was feeling almost normal, when I came down with a sinus infection. On Monday, I went to the doctor. I was given a sinus cocktail shot, which contains benadryl and steroids, and cefzil which is an antibiotic. By Tues afternoon, I was starting to feel nervous and antsy. Now, Wed morning, I am very sleepy, shaky, crying and feel like I am jumping out of my skin. Does this sound like a reaction to the steroid in the sinus cocktail shot, or to the antibiotic? It has me worried that I am having another spell.... has anyone ever had this type of reaction?