help is my damage irersable....?

dear doctort hank you so much for chatting with me.. i live alone with to kids 6 and 7 years with no familey support...... i was on low dose 37.5 velafaxcine for 5 years untill they stopped having effect on my anxiety but my depresion was mangeble i never lost my intrests or since of humor when it was increased to 75mg thats when i started feeling depersonlized and more anxiety and more depresed but doc said side effect will go.. trusting him taking it further altogether 5 weeks which i was screaming for help i had all the mentel signs of taking a LSD. (which i never have) i didnt know who i was were i was what planet i was on and lots of scarey thoughts doc just told me to miss one day then start taking new sertraline 50mg was 15th november 2010 i felt overwelmed with all sorts of emotions and thoughts i couldnt make sence of. for a few days then was very emotionly blunted and living in a dream... not only that but day befor felt like a dream, my past life felt like a dream im very unsetteled  feel tensed all the time..no focus, no concertration short and long term memory is very bad, i find it very hard to make the simplest dicisions and when i do try to concertrate or try to remember somethink it hurts mentaly and psyicaly in my head at night i try to deep breathing to relax but find it hard to imagen a happy place its hard to . i get depresed because i miss the old happy out going loving me and i want my appertite for food back and my intrest in all enjoyable things like fashon shopping and pride over myself, my home and my kids back.. i hate feeling numb inside...... im taking is my sertraline and vitamin b compond.  sorry about all spelly mistakes i seem to rush to chat to get it all out... thank you for listening to me..... please could u let me know is there any long term damage from this bad reaction i had..? which was very trumatic its been just over 3 months now and still feel same im very sencative to tablets because of my enzimes in my liver ........ also if an antidepresant had worked for me before would it work for me again.?

thanks tracy

[Paxiled]

There are no doctors on this forum, just fellow sufferers.  I don't know if there's an expert forum anymore where a doctor answers questions.  I can tell you that nobody knows if an antidepressant will work again for you -- sometimes they do, sometimes they don't.  I don't think your doctor knows anything about these meds and how they work -- is it an experienced caring psychiatrist, or just a regular doc?  Because I assume you mean you were on Effexor, which is a very difficult med, but any med is at its worst with side effects when the dosage is changed, either up or down.  With such an extreme reaction, the dosage should have been lowered back to where you were comfortable, and then options discussed.  You also don't indicate whether you tapered off the Effexor, or were just switched to Zoloft.  Effexor is known for being very difficult to quit, and so it is best to slowly taper off it.  Switching to Zoloft, a medication in a different class, won't necessarily do anything about Effexor withdrawal.  As for long term damage, that's a sore spot for medical professionals, because yes, it can happen, but usually only when mistakes are made by the doctor, and it's not very common.  Just assume there's no long-term damage, and find a very knowledgeable psychiatrist as quickly as possible who knows how to withdraw you from medication and how to properly switch medications.  If you don't like what you're hearing, find a different psychiatrist.  Good luck.